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Details for Product No. ABIN183798

GATA Zinc Finger Domain Containing 2B (GATAD2B) (N-Term) antibody

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Antigen
Synonyms MRD18, P66beta, RP11-216N14.6, p68, RGD1308533, AL118180, C430014D17Rik, mKIAA1150, GATAD2B
Epitope
»Alternatives N-Term
Reactivity
»Alternatives Mouse (Murine), Rat (Rattus), Dog (Canine), Cow (Bovine), Zebrafish (Danio rerio), Human
Host
»Alternatives Rabbit
Clonality Polyclonal
Application
»Alternatives Western Blotting (WB)
Pubmed 1 reference available
Catalog no. ABIN183798
Quantity 50 µg
Price
289.00 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen The immunogen for anti-GATAD2B antibody: synthetic peptide directed towards the N terminal of human GATAD2B
Sequence MDRMTEDALRLNLLKRSLDPADERDDVLAKRLKMEGHEAM ERLKMLALLK
Predicted Reactivity Bovine : 100%, Dog : 100%, Guinea pig : 100%, Horse : 100%, Mouse : 100%, Pig : 100%, Rabbit : 100%, Rat : 100%
Characteristics This is a rabbit polyclonal antibody against GATAD2B. It was validated on Western Blot using a cell lysate as a positive control. We strive to provide antibodies covering each member of a whole protein family of your interest.
Purification Affinity Purified
Alternative Name GATAD2B
Background Hp66beta (GATAD2B), previously identified as a component of the human MeCP1 complex, is a second member of a p66 gene family (hp66alpha and hp66beta). Both proteins interact with MBD2 and MBD3 functionally and biochemically. Both factors function in synergy, since knocking-down p66alpha affects the repressive function of p66beta and vice versa. Furthermore, confocal microscopy shows a nuclear colocalization of hp66alpha with hp66beta and MBD2 in a speckled pattern. These two highly related mammalian p66 proteins display overlapping functions and are involved in methylation dependent transcriptional repression.
Molecular Weight 65kDa
Gene ID 57459
NCBI Accession NP_065750, NM_020699
UniProt Q8WXI9
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water
Concentration 1mg/mL
Buffer Final anti-GATAD2B antibody concentration is 1 mg/mL in PBS buffer.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Background publications Beausoleil, Jedrychowski, Schwartz et al.: "Large-scale characterization of HeLa cell nuclear phosphoproteins." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 33, pp. 12130-5, 2004 (PubMed).

Alternatives for antigen "GATA Zinc Finger Domain Containing 2B (GATAD2B)", type "Antibodies"
Hosts (20), (8), (2)
Reactivities (26), (9), (2), (2), (2)
Applications (27), (9), (6), (3), (3), (2)
Epitopes (8), (3), (3), (3), (2), (1), (1), (1), (1), (1), (1)
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