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GATA Zinc Finger Domain Containing 2B (GATAD2B) (N-Term) antibody

Details for Product No. ABIN183798
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Antigen
Synonyms GATAD2B, MRD18, P66beta, RP11-216N14.6, p68, AL118180, C430014D17Rik, mKIAA1150, RGD1308533
Epitope
N-Term
(13), (9), (9), (3), (3), (3), (2), (2), (2), (1), (1)
Reactivity
Mouse (Murine), Rat (Rattus), Dog (Canine), Cow (Bovine), Zebrafish (Danio rerio), Human
(31), (15), (2), (2), (2)
Host
Rabbit
(26), (14), (2)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2), (2), (2), (2), (2)
Application
Western Blotting (WB)
(38), (18), (5), (5), (5), (3)
Pubmed 1 reference available
Quantity 50 µg
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Catalog No. ABIN183798
289.00 $
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Immunogen Synthetic peptide directed towards the N terminal of human GATAD2B
Sequence MDRMTEDALRLNLLKRSLDPADERDDVLAKRLKMEGHEAM ERLKMLALLK
Predicted Reactivity Bovine : 100 %, Dog : 100 %, Guinea pig : 100 %, Horse : 100 %, Mouse : 100 %, Pig : 100 %, Rabbit : 100 %, Rat : 100 %
Characteristics This is a rabbit polyclonal antibody against GATAD2B. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name GATAD2B
Background Hp66beta (GATAD2B), previously identified as a component of the human MeCP1 complex, is a second member of a p66 gene family (hp66alpha and hp66beta). Both proteins interact with MBD2 and MBD3 functionally and biochemically. Both factors function in synergy, since knocking-down p66alpha affects the repressive function of p66beta and vice versa. Furthermore, confocal microscopy shows a nuclear colocalization of hp66alpha with hp66beta and MBD2 in a speckled pattern. These two highly related mammalian p66 proteins display overlapping functions and are involved in methylation dependent transcriptional repression.
Molecular Weight 65 kDa
Gene ID 57459
NCBI Accession NM_020699, NP_065750
UniProt Q8WXI9
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 593 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-GATA Zinc Finger Domain Containing 2B (GATAD2B) (N-Term) antibody WB Suggested Anti-GATAD2B Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: HepG2 cell lysate
Background publications Beausoleil, Jedrychowski, Schwartz et al.: "Large-scale characterization of HeLa cell nuclear phosphoproteins." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 33, pp. 12130-5, 2004 (PubMed).

Validation Images
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