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KRT18 antibody (Keratin 18) (N-Term)

Details for Product anti-KRT18 Antibody No. ABIN183896, Supplier: Login to see New
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Antigen
Alternatives
Epitope
N-Term
(62), (27), (22), (13), (13), (13), (12), (10), (9), (9), (6), (6), (5), (5), (5), (5), (4), (4), (4), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Rat (Rattus), Xenopus laevis
(621), (112), (98), (30), (19), (17), (15), (13), (11), (9), (8), (6), (5), (5), (4), (3), (3), (3), (3), (3), (3), (2), (1), (1), (1)
Host
Rabbit
(368), (287), (10), (9), (6), (3)
Clonality
Polyclonal
Conjugate
This KRT18 antibody is un-conjugated
(41), (40), (9), (6), (4), (4), (3), (3), (3), (3), (3), (3), (1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (IHC), Western Blotting (WB)
(451), (258), (236), (173), (168), (127), (101), (101), (58), (36), (18), (13), (11), (3), (2), (2), (1), (1), (1)
Pubmed 1 reference available
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Quantity 100 μg
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Immunogen Synthetic peptide directed towards the N terminal of human KRT18
Sequence TRSTFSTNYR SLGSVQAPSY GARPVSSAAS VYAGAGGSGS RISVSRSTSF
Predicted Reactivity Human : 100 %, Dog : 90 %, Bovine : 80 %
Characteristics This is a rabbit polyclonal antibody against KRT18. It was validated on Western Blot and immunohistochemistry.
Purification Protein A purified
Alternative Name KRT18 (KRT18 Antibody Abstract)
Background KRT18 (Keratin 18) is type I intermediate filament chain. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis.KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene.
Molecular Weight 47 kDa
Gene ID 3875
NCBI Accession NP_000215, NM_000224
UniProt P05783
Pathways Apoptosis, Caspase Cascade in Apoptosis
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 430 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
Western Blotting (WB) image for anti-KRT18 antibody (Keratin 18) (N-Term) (ABIN183896) WB Suggested Anti-KRT18 Antibody Titration: 1.25ug/ml
ELISA Titer: 1...
Immunohistochemistry (IHC) image for anti-KRT18 antibody (Keratin 18) (N-Term) (ABIN183896) anti-Keratin 18 (KRT18) (N-Term) antibody (Image 2)
Western Blotting (WB) image for anti-KRT18 antibody (Keratin 18) (N-Term) (ABIN183896) WB Suggested Anti-KRT18
Antibody Titration: 1.25 µg/mL ELISA Titer: 1:1562500 ...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-KRT18 antibody (Keratin 18) (N-Term) (ABIN183896) Rabbit Anti-KRT18 Antibody ,Paraffin Embedded Tissue: Human alveolar cell
Cell...
Background publications Ku, Lim, Krams et al.: "Keratins as susceptibility genes for end-stage liver disease." in: Gastroenterology, Vol. 129, Issue 3, pp. 885-93, 2005 (PubMed).

Catalog No. ABIN183896

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