Ribosomal Protein L6 (RPL6) (N-Term) antibody

Details for Product No. ABIN183900
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Antigen
Synonyms L6, SHUJUN-2, TAXREB107, TXREB1, Taxreb107
Epitope
N-Term
(1), (1), (1), (1), (1), (1)
Reactivity
Dog (Canine), Mouse (Murine), Rat (Rattus), Cow (Bovine), Pig (Porcine), Human
(10), (2), (2), (1)
Host
Rabbit
(9), (1)
Clonality
Polyclonal
Application
Western Blotting (WB)
(10), (3), (2), (2), (2), (2), (1)
Pubmed 1 reference available
Quantity 100 μg
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Catalog No. ABIN183900
229.00 $
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Immunogen Synthetic peptide directed towards the N terminal of human RPL6
Sequence AGEKVEKPDT KEKKPEAKKV DAGGKVKKGN LKAKKPKKGK PHCSRNPVLV
Predicted Reactivity Bovine : 100 %, Dog : 100 %, Human : 100 %, Mouse : 80 %, Rat : 70 %
Characteristics This is a rabbit polyclonal antibody against RPL6. It was validated on Western Blot using a cell lysate as a positive control.
Purification Protein A purified
Alternative Name RPL6
Background RPL6 is a ribosomal protein that is a component of the 60S subunit. RPL6 belongs to the L6E family of ribosomal proteins. It is located in the cytoplasm. The protein can bind specifically to domain C of the tax-responsive enhancer element of human T-cell leukemia virus type 1, and it has been suggested that the protein may participate in tax-mediated transactivation of transcription. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L6E family of ribosomal proteins. It is located in the cytoplasm. The protein can bind specifically to domain C of the tax-responsive enhancer element of human T-cell leukemia virus type 1, and it has been suggested that the protein may participate in tax-mediated transactivation of transcription. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.
Molecular Weight 32 kDa
Gene ID 6128
NCBI Accession NP_001019833, NM_001024662
UniProt Q02878
Research Area Chromatin and Nuclear Signaling, Transcription Factors, DNA/RNA
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 288 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-Ribosomal Protein L6 (RPL6) (N-Term) antibody WB Suggested Anti-RPL6 Antibody Titration: 2.5ug/ml
ELISA Titer: 1:62500
Positive Control: Jurkat cell lysate
anti-Ribosomal Protein L6 (RPL6) (N-Term) antibody (2) WB Suggested Anti-RPL6
Antibody Titration: 2.5 µg/mL ELISA Titer: 1:.2500
Positive Control: Jurkat cell lysate
RPL6 is supported by BioGPS gene expression data to be expressed in Jurkat
Background publications Bouwmeester, Bauch, Ruffner et al.: "A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway. ..." in: Nature cell biology, Vol. 6, Issue 2, pp. 97-105, 2004 (PubMed).

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