Retinoic Acid Receptor, alpha (RARA) (N-Term) antibody

Details for Product No. ABIN183927
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Antigen
Synonyms rar-alpha, nr1b1, NR1B1, RAR, Nr1b1, RARalpha1, HS-RARa, rara2a, RAR-ALPHA1
Epitope
N-Term
(19), (16), (15), (11), (8), (7), (7), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Mouse (Murine), Rat (Rattus), Human
(112), (58), (50), (6), (5), (1), (1), (1)
Host
Rabbit
(80), (32), (6)
Clonality
Polyclonal
Conjugate
Un-conjugated
(3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(109), (65), (42), (22), (15), (11), (10), (8), (4), (3), (2), (1), (1), (1)
Pubmed 1 reference available
Quantity 100 μg
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Catalog No. ABIN183927
229.00 $
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Immunogen Synthetic peptide directed towards the N terminal of human RARA
Sequence TPNPFLVVDF YNQNRACLLP EKGLPAPGPY STPLRTPLWN GSNHSIETQS
Predicted Reactivity Human : 100 %, Mouse : 90 %, Rat : 90 %
Characteristics This is a rabbit polyclonal antibody against RARA. It was validated on Western Blot using a cell lysate as a positive control.
Purification Protein A purified
Alternative Name RARA
Background RARA contains 1 nuclear receptor DNA-binding domain and belongs to the nuclear hormone receptor family, NR1 subfamily. It is a receptor for retinoic acid. This metabolite has profound effects on vertebrate development. Retinoic acid is a morphogen and is a powerful teratogen. This receptor controls cell function by directly regulating gene expression
Molecular Weight 50 kDa
Gene ID 5914
NCBI Accession NM_001024809, NP_001019980
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 457 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-Retinoic Acid Receptor, alpha (RARA) (N-Term) antibody WB Suggested Anti-RARA Antibody Titration: 1.25ug/ml
ELISA Titer: 1:1562500
Positive Control: Jurkat cell lysate
anti-Retinoic Acid Receptor, alpha (RARA) (N-Term) antibody (2) WB Suggested Anti-RARA
Antibody Titration: 1.25 µg/mL ELISA Titer: 1:1562500
Positive Control: Jurkat cell lysate
There is BioGPS gene expression data showing that RARA is expressed in Jurkat
Background publications Srinivas, Xia, Moore et al.: "Akt phosphorylates and suppresses the transactivation of retinoic acid receptor alpha." in: The Biochemical journal, Vol. 395, Issue 3, pp. 653-62, 2006 (PubMed).

Validation Images
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