EIF4A2 antibody (N-Term)

Catalog No. ABIN183941

Product Details anti-EIF4A2 Antibody

Target: EIF4A2 (Eukaryotic Translation Initiation Factor 4A2 (EIF4A2))

Binding Specificity: N-Term

Reactivity: Human, Rat, Mouse, Dog, Pig, Cow, Rabbit, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EIF4A2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MSGGSADYNR EHGGPEGMDP DGVIESNWNE IVDNFDDMNL KESLLRGIYA

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against EIF4A2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human EIF4A2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 407 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for EIF4A2

Target: EIF4A2 (Eukaryotic Translation Initiation Factor 4A2 (EIF4A2))

Alternative Name: EIF4A2 (EIF4A2 Products)

Synonyms: BM-010 antibody, DDX2B antibody, EIF4A antibody, EIF4F antibody, eIF-4A-II antibody, eIF4A-II antibody, 4833432N07Rik antibody, Ddx2b antibody, Eif4 antibody, ddx2b antibody, eif4aii antibody, eif4f antibody, xeif4aii antibody, EIF4A2 antibody, EIF4AII antibody, wu:fd50g11 antibody, zgc:63783 antibody, eukaryotic translation initiation factor 4A2 antibody, eukaryotic translation initiation factor 4A2 L homeolog antibody, microRNA 1248 antibody, eukaryotic translation initiation factor 4A, isoform 2 antibody, Eif4a2 antibody, EIF4A2 antibody, eif4a2.L antibody, eif4a2 antibody, MIR1248 antibody

Background: EIF4A2 contains 1 helicase C-terminal domain and 1 helicase ATP-binding domain. It belongs to the DEAD box helicase family. eIF4A subfamily. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5' untranslated region of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.
Alias Symbols: DDX2B, EIF4A, EIF4F, BM-010, eIF4A-II, eIF-4A-II
Protein Interaction Partner: SLC16A9, PIH1D2, SSX2IP, TRIM39, TRIM36, DPPA4, IPO11, PDCD4, MDFI, EIF4A2, SUMO2, SUMO3, UBC, BAG3, CD81, VCP, ECT2, BRCA1, EIF4G3, DDX39B, EIF4A1, SUMO1, TK1, PFDN1, NEK2, Eif3a, CD4, RPAP2, EIF3F, EIF4G2, EIF4G1, CLNS1A, RPS29, CMBL, VAC14, EIF3L, EIF3
Protein Size: 407

Molecular Weight: 45 kDa

Gene ID: 1974

NCBI Accession: NM_001967, NP_001958

UniProt: Q14240