SRP19 antibody (Middle Region)

Catalog No. ABIN183959

Product Details anti-SRP19 Antibody

Target: SRP19 (Signal Recognition Particle 19kDa (SRP19))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Rabbit, Zebrafish (Danio rerio), Cow, Dog, Horse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SRP19 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: LCLVQFPSRK SVMLYAAEMI PKLKTRTQKT GGADQSLQQG EGSKKGKGKK

Predicted Reactivity: Cow: 93%, Dog: 93%, Horse: 93%, Human: 100%, Mouse: 92%, Pig: 93%, Rabbit: 85%, Rat: 92%, Zebrafish: 77%

Characteristics: This is a rabbit polyclonal antibody against SRP19. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SRP19

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 144 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-SRP19 antibody (ABIN183959)

Arana-Argáez, Delgado-Rizo, Pizano-Martínez, Martínez-Garcia, Martín-Márquez, Muñoz-Gómez, Petri, Armendáriz-Borunda, Espinosa-Ramírez, Zúñiga-Tamayo, Herrera-Esparza, Vázquez-Del Mercado: "Inhibitors of MAPK pathway ERK1/2 or p38 prevent the IL-1{beta}-induced up-regulation of SRP72 autoantigen in Jurkat cells." in: The Journal of biological chemistry, Vol. 285, Issue 43, pp. 32824-33, (2010) (PubMed).

Target Details for SRP19

Target: SRP19 (Signal Recognition Particle 19kDa (SRP19))

Alternative Name: SRP19 (SRP19 Products)

Synonyms: 2310020D23Rik antibody, zgc:63961 antibody, CG4457 antibody, Dmel\\CG4457 antibody, SRP19 antibody, srp19 antibody, signal recognition particle 19 antibody, signal recognition particle 19kDa L homeolog antibody, signal recognition particle 19kDa antibody, Signal recognition particle protein 19 antibody, SRP19 antibody, srp19.L antibody, srp19 antibody, Srp19 antibody

Background: SRP19 belongs to the SRP19 family. It is signal-recognition-particle assembly and binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP.
Protein Interaction Partner: STAM2, ACTN1, BAG3, SMN1, MDN1, ZC3H11A, EIF4A3, ZFAND5, UBC, IPO8, IPO7, SRP54, TNPO1, KPNA1, IPO5,
Protein Size: 144

Molecular Weight: 16 kDa

Gene ID: 6728

NCBI Accession: NM_003135, NP_003126

UniProt: P09132

Pathways: SARS-CoV-2 Protein Interactome