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Interleukin enhancer-binding factor 3 (ILF3) (N-Term) antibody

ILF3 Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Horse WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN183971
  • Target See all Interleukin enhancer-binding factor 3 (ILF3) Antibodies
    Interleukin enhancer-binding factor 3 (ILF3)
    Binding Specificity
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 57
    • 40
    • 37
    • 14
    • 11
    • 11
    • 10
    • 5
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Horse
    Host
    • 53
    • 2
    • 1
    Rabbit
    Clonality
    • 46
    • 11
    Polyclonal
    Conjugate
    • 43
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Un-conjugated
    Application
    • 37
    • 17
    • 11
    • 10
    • 9
    • 9
    • 5
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    ALKAVSDWID EQEKGSSEQA ESDNMDVPPE DDSKEGAGEQ KTEHMTRTLR
    Predicted Reactivity
    Cow: 86%, Dog: 86%, Guinea Pig: 79%, Horse: 93%, Human: 100%, Mouse: 79%, Rabbit: 86%, Rat: 79%
    Characteristics
    This is a rabbit polyclonal antibody against ILF3. It was validated on Western Blot and immunohistochemistry.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human ILF3
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    Discover our top product ILF3 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 702 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    Interleukin enhancer-binding factor 3 (ILF3)
    Alternative Name
    ILF3 (ILF3 Products)
    Synonyms
    CBTF antibody, DRBF antibody, DRBP76 antibody, MMP4 antibody, MPHOSPH4 antibody, MPP4 antibody, NF-AT-90 antibody, NF110 antibody, NF110b antibody, NF90 antibody, NF90a antibody, NF90b antibody, NFAR antibody, NFAR-1 antibody, NFAR2 antibody, TCP110 antibody, TCP80 antibody, MBII-26 antibody, ilf3 antibody, wu:fb37d07 antibody, wu:fb94b02 antibody, zgc:77030 antibody, 4F.1 antibody, cbtf122 antibody, ilf3-A antibody, ubp3 antibody, ubp4 antibody, xilf3 antibody, interleukin enhancer binding factor 3 antibody, interleukin enhancer binding factor 3b antibody, interleukin enhancer binding factor 3 S homeolog antibody, ILF3 antibody, Ilf3 antibody, ilf3b antibody, ilf3.S antibody
    Background
    ILF3 may facilitate double-stranded RNA-regulated gene expression at the level of post-transcription. ILF3 can act as a translation inhibitory protein which binds to coding sequences of acid beta-glucosidase (GCase) and other mRNAs and functions at the initiation phase of GCase mRNA translation, probably by inhibiting its binding to polysomes. ILF3 can regulate protein arginine N-methyltransferase 1 activity. ILF3 may regulate transcription of the IL2 gene during T-cell activation. It can promote the formation of stable DNA-dependent protein kinase holoenzyme complexes on DNA.Nuclear factor of activated T-cells (NFAT) is a transcription factor required for T-cell expression of interleukin 2. NFAT binds to a sequence in the IL2 enhancer known as the antigen receptor response element 2. In addition, NFAT can bind RNA and is an essential component for encapsidation and protein priming of hepatitis B viral polymerase. NFAT is a heterodimer of 45 kDa and 90 kDa proteins, the larger of which is the product of this gene. The encoded protein, which is primarily localized to ribosomes, probably regulates transcription at the level of mRNA elongation. At least three transcript variants encoding three different isoforms have been found for this gene.Nuclear factor of activated T-cells (NFAT) is a transcription factor required for T-cell expression of interleukin 2. NFAT binds to a sequence in the IL2 enhancer known as the antigen receptor response element 2. In addition, NFAT can bind RNA and is an essential component for encapsidation and protein priming of hepatitis B viral polymerase. NFAT is a heterodimer of 45 kDa and 90 kDa proteins, the larger of which is the product of this gene. The encoded protein, which is primarily localized to ribosomes, probably regulates transcription at the level of mRNA elongation. At least three transcript variants encoding three different isoforms have been found for this gene.
    Alias Symbols: CBTF, DRBF, MMP4, MPP4, NF90, NFAR, NF110, NF90a, NF90b, NFAR2, TCP80, DRBP76, NF110b, NFAR-1, TCP110, MPHOSPH4, NF-AT-90
    Protein Interaction Partner: PLSCR1, UBC, FBXW11, RBPMS, HUWE1, MDM2, AURKA, SUMO2, SUMO3, STAU1, IVNS1ABP, LGR4, ERG, RPA3, RPA2, RPA1, EZH2, HNRNPL, SUZ12, RNF2, BMI1, EED, VHL, VEGFA, rev, FBXO6, TARDBP, CSF2, EIF2AK2, ICAM1, IGSF8, SNORD116-22, PABPC1, RNU2-4P, RNU5B-1, RNU5A-1,
    Protein Size: 702
    Molecular Weight
    76 kDa
    Gene ID
    3609
    NCBI Accession
    NM_004516, NP_004507
    Pathways
    M Phase
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