CDK4 antibody (C-Term)

Catalog No. ABIN184132

Product Details anti-CDK4 Antibody

Target: CDK4 (Cyclin-Dependent Kinase 4 (CDK4))

Binding Specificity: C-Term

Reactivity: Human, Rat, Sheep, Pig, Dog, Cow, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDK4 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: PRPVQSVVPE MEESGAQLLL EMLTFNPHKR ISAFRALQHS YLHKDEGNPE

Predicted Reactivity: Cow: 78%, Dog: 85%, Human: 100%, Pig: 92%, Rabbit: 85%, Rat: 78%, Sheep: 78%

Characteristics: This is a rabbit polyclonal antibody against CDK4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CDK4

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 303 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CDK4

Target: CDK4 (Cyclin-Dependent Kinase 4 (CDK4))

Alternative Name: CDK4 (CDK4 Products)

Synonyms: zgc:153726 antibody, CMM3 antibody, PSK-J3 antibody, Crk3 antibody, 8-6 antibody, CDK4 antibody, CDK4/6 antibody, CG5072 antibody, Cdk4/6 antibody, DmCdk4 antibody, Dmel\\CG5072 antibody, Pk53C antibody, Pk?7 antibody, cdk antibody, cdk4 antibody, cdk4/6 antibody, dCdk4 antibody, l(2)05428 antibody, l(2)0671 antibody, l(2)k06503 antibody, l(2)s4639 antibody, l(2)sh0671 antibody, xcdk4 antibody, cyclin-dependent kinase 4 antibody, cyclin dependent kinase 4 antibody, Cyclin-dependent kinase 4 antibody, cyclin-dependent kinase 4 L homeolog antibody, cdk4 antibody, CDK4 antibody, Cdk4 antibody, cdk4.L antibody

Background: Cdk4 is probably involved in the control of the cell cycle.
Alias Symbols: CMM3, PSK-J3
Protein Interaction Partner: RELA, HOOK1, CDKN2D, CDKN2C, CCND3, CCND1, CDKN1A, CCNA2, FKBP5, CDC37, CDKN1B, CDK4, UBC, CDKN2B, CDKN2A, CDK13, TARDBP, CAMK1, PTMA, CDK6, RB1, HSP90AB1, HSP90AA1, HSPA8, KLHL32, TRAP1, UCHL1, SKP1, SHOX2, RBL2, RBL1, PGD, OTX2, MYC, MCM2, IL15RA, GLI1,
Protein Size: 303

Molecular Weight: 34 kDa

Gene ID: 1019

NCBI Accession: NM_000075, NP_000066

UniProt: P11802

Pathways: Cell Division Cycle, Mitotic G1-G1/S Phases, Regulation of Cell Size