SREBF2 antibody (Middle Region)

Catalog No. ABIN184207

Product Details anti-SREBF2 Antibody

Target: SREBF2 (Sterol Regulatory Element Binding Transcription Factor 2 (SREBF2))

Binding Specificity: Middle Region

Reactivity: Human, Rat, Dog, Cow, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SREBF2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: PASDSGSQAG FSPYSIDSEP GSPLLDDAKV KDEPDSPPVA LGMVDRSRIL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against SREBF2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SREBF2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1141 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SREBF2

Target: SREBF2 (Sterol Regulatory Element Binding Transcription Factor 2 (SREBF2))

Alternative Name: SREBF2 (SREBF2 Products)

Synonyms: SREBF2 antibody, srebp2 antibody, SREBP2 antibody, zgc:158371 antibody, AI608257 antibody, SREBP-2 antibody, SREBP2gc antibody, bHLHd2 antibody, lop13 antibody, nuc antibody, Srebf2_retired antibody, sterol regulatory element binding transcription factor 2 antibody, sterol regulatory element binding factor 2 antibody, sterol regulatory element binding transcription factor 2 L homeolog antibody, SREBF2 antibody, srebf2 antibody, Srebf2 antibody, srebf2.L antibody

Background: SREBF2 is a ubiquitously expressed transcription factor that controls cholesterol homeostasis by stimulating transcription of sterol-regulated genes. This gene encodes a ubiquitously expressed transcription factor that controls cholesterol homeostasis by stimulating transcription of sterol-regulated genes. The encoded protein contains a basic helix-loop-helix-leucine zipper (bHLH-Zip) domain. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: SREBP2, bHLHd2
Protein Interaction Partner: UBC, ERLIN2, MRPS6, NAE1, MAPK3, MAPK1, PARK7, SCAP, SREBF2, SREBF1, NPAT, HINFP, TRRAP, SUMO2, RNF139, SMAD3, HNF4A, ATF6, KLF13, LZTR1, ABLIM2, ATF7IP, ZDHHC17, COPS5, OS9, PIAS3, CASP8AP2, ARHGEF1, PIAS2, SLC4A4, PIAS1, ZYX, ZMYM2, UBE2I, TTC1, SPTBN1,
Protein Size: 1141

Molecular Weight: 124 kDa

Gene ID: 6721

NCBI Accession: NM_004599, NP_004590

UniProt: Q12772

Pathways: Regulation of Lipid Metabolism by PPARalpha