CHRNE antibody (N-Term)

Catalog No. ABIN184225

Product Details anti-CHRNE Antibody

Target: CHRNE (Cholinergic Receptor, Nicotinic, epsilon (Muscle) (CHRNE))

Binding Specificity: N-Term

Reactivity: Mouse, Rat, Guinea Pig, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHRNE antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: GLLGRGVGKN EELRLYHHLF NNYDPGSRPV REPEDTVTIS LKVTLTNLIS

Predicted Reactivity: Guinea Pig: 84%, Mouse: 91%, Pig: 80%, Rat: 91%

Characteristics: This is a rabbit polyclonal antibody against CHRNE. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CHRNE

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 493 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CHRNE

Target: CHRNE (Cholinergic Receptor, Nicotinic, epsilon (Muscle) (CHRNE))

Alternative Name: CHRNE (CHRNE Products)

Synonyms: ACHRE antibody, CMS1D antibody, CMS1E antibody, CMS2A antibody, FCCMS antibody, SCCMS antibody, AChrepsilon antibody, Acre antibody, nAChRE antibody, im:7154697 antibody, zgc:101010 antibody, CHRNE antibody, cholinergic receptor nicotinic epsilon subunit antibody, cholinergic receptor, nicotinic, epsilon polypeptide antibody, cholinergic receptor, nicotinic epsilon L homeolog antibody, cholinergic receptor, nicotinic, epsilon antibody, CHRNE antibody, Chrne antibody, chrne.L antibody, chrne antibody

Background: After binding acetylcholine, the ACHR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
Alias Symbols: ACHRE, CMS1D, CMS1E, CMS2A, FCCMS, SCCMS
Protein Interaction Partner: CHRNA1,
Protein Size: 493

Molecular Weight: 55 kDa

Gene ID: 1145

NCBI Accession: NM_000080, NP_000071

UniProt: Q04844