RAB3A, Member RAS Oncogene Family (RAB3A) (C-Term) antibody

Details for Product No. ABIN184247
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Antigen
Synonyms rab3a, zgc:92276, gov, d2-2, rab16, rad3d, MGC69316, MGC130815, RAB3A, rab-3a, RAB3, si:ch211-255d18.4, zgc:112516
Epitope
C-Term
(17), (8), (7), (6), (4), (4), (2), (2), (2), (1), (1)
Reactivity
Mouse (Murine), Rat (Rattus), Dog (Canine), Cow (Bovine), Pig (Porcine), Xenopus laevis, Human
(71), (45), (39), (15), (15), (14), (4), (3), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Host
Rabbit
(59), (18), (2)
Clonality
Polyclonal
Conjugate
Un-conjugated
(5), (5), (5), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2)
Application
Western Blotting (WB)
(60), (28), (20), (14), (12), (10), (4), (3), (1)
Pubmed 1 reference available
Quantity 100 µg
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Catalog No. ABIN184247
229.00 $
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Immunogen Synthetic peptide directed towards the C terminal of human RAB3A
Sequence NVKQTFERLV DVICEKMSES LDTADPAVTG AKQGPQLSDQ QVPPHQDCAC
Predicted Reactivity Human : 100 %, Bovine : 80 %, Dog : 80 %, Guinea pig : 80 %, Mouse : 80 %, Pig : 80 %, Rat : 80 %, Sheep : 80 %, African clawed frog : 80 %
Characteristics This is a rabbit polyclonal antibody against RAB3A. It was validated on Western Blot using a cell lysate as a positive control.
Purification Protein A purified
Alternative Name RAB3A
Background RAB3A is involved in exocytosis by regulating a late step in synaptic vesicle fusion. It could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal.
Molecular Weight 25 kDa
Gene ID 5864
NCBI Accession NM_002866, NP_002857
UniProt P20336
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 220 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-RAB3A, Member RAS Oncogene Family (RAB3A) (C-Term) antibody Sample Type: Human brain
Secondary Antibody: TIgG product, 1.25ug/ml
anti-RAB3A, Member RAS Oncogene Family (RAB3A) (C-Term) antibody (2) Sample Type: 1. Human Cervical Cancer Cell Lysate (15ug)
2. Monkey Fibroblast Cell Lysate (15ug)
3. Human Cervical Cancer Cell transfected with mouse Rab3A-GFP (15ug)
Primary Dilution: 1:1000
Secondary Antibody: goat anti-Rabbit
Secondary Dilution: 1:40,000
Image Submitted by: Dr. Jakob Szwedo, Dr. Lupashin's Lab
University of Arkansas for Medical Sciences.

Background publications Zahraoui, Touchot, Chardin et al.: "The human Rab genes encode a family of GTP-binding proteins related to yeast YPT1 and SEC4 products involved in secretion." in: The Journal of biological chemistry, Vol. 264, Issue 21, pp. 12394-401, 1989 (PubMed).

Validation Images
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