CHRNA2 antibody (N-Term)

Catalog No. ABIN184249

Product Details anti-CHRNA2 Antibody

Target: CHRNA2 (Cholinergic Receptor, Nicotinic, alpha 2 (Neuronal) (CHRNA2))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHRNA2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: TKLSLWWLLL TPAGGEEAKR PPPRAPGDPL SSPSPTALPQ GGSHTETEDR

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against CHRNA2. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CHRNA2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 529 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CHRNA2

Target: CHRNA2 (Cholinergic Receptor, Nicotinic, alpha 2 (Neuronal) (CHRNA2))

Alternative Name: CHRNA2 (CHRNA2 Products)

Synonyms: CHRNA2 antibody, NACHRA2 antibody, chrna2 antibody, zgc:136717 antibody, ACHR antibody, Acra-2 antibody, Acra2 antibody, BC011490 antibody, cholinergic receptor nicotinic alpha 2 subunit antibody, cholinergic receptor, nicotinic, alpha 2a (neuronal) antibody, cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal) antibody, neuronal acetylcholine receptor subunit alpha-2 antibody, neuronal acetylcholine receptor subunit alpha-4-like antibody, CHRNA2 antibody, chrna2a antibody, Chrna2 antibody, CpipJ_CPIJ002436 antibody, LOC100370261 antibody, Tsp_10995 antibody

Background: After binding acetylcholine, the ACHR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
Protein Interaction Partner: CHRNB4, CHRNB2,
Protein Size: 529

Molecular Weight: 60 kDa

Gene ID: 1135

NCBI Accession: NM_000742, NP_000733

UniProt: Q15822