ERG antibody (Middle Region)

Catalog No. ABIN184274

Product Details anti-ERG Antibody

Target: ERG (ERG, ETS transcription factor (ERG))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ERG antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: ARNTDLPYEP PRRSAWTGHG HPTPQSKAAQ PSPSTVPKTE DQRPQLDPYQ

Cross-Reactivity: Cow (Bovine), Chicken, Human, Mouse (Murine), Rat (Rattus)

Predicted Reactivity: Cow: 100%, Dog: 92%, Guinea Pig: 85%, Horse: 100%, Human: 100%, Mouse: 92%, Rabbit: 92%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against ERG. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ERG

Application Details

Application Notes: WB Suggested Anti-ERG Antibody Titration: 1.0 µg/mL
Positive Control: Jurkat cell lysate.
Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 462 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ERG

Target: ERG (ERG, ETS transcription factor (ERG))

Alternative Name: ERG (ERG Products)

Synonyms: erg-3 antibody, p55 antibody, erg antibody, erg_A antibody, zgc:103429 antibody, erg_E antibody, ERG antibody, D030036I24Rik antibody, KCNH2 antibody, ERG, ETS transcription factor antibody, v-ets avian erythroblastosis virus E26 oncogene homolog L homeolog antibody, v-ets avian erythroblastosis virus E26 oncogene homolog antibody, v-ets avian erythroblastosis virus E26 oncogene homolog S homeolog antibody, ETS transcription factor antibody, potassium voltage-gated channel subfamily H member 6 antibody, ERG antibody, Erg antibody, erg.L antibody, erg antibody, erg.S antibody, KCNH6 antibody

Background: V-ets erythroblastosis virus E26 oncogene like isoform 2 (ERG) is a transcriptional regulator. It may participate in transcriptional regulation through the recruitment of SETDB1 histone methyltransferase and subsequent modification of local chromatin structure.
Alias Symbols: p55, erg-3
Protein Interaction Partner: UBC, SFPQ, RPLP0, PRKDC, POLR2A, PCBP1, NUMA1, NPM1, NONO, NCL, ILF3, ILF2, HSPD1, HNRNPU, HNRNPH3, HNRNPH1, HNRNPF, HNRNPD, HNRNPC, HNRNPAB, HNRNPA2B1, HNRNPA1, FBL, ELAVL1, EEF1A2, DKC1, CLTC, CDC5L, HNRNPUL2, RCC2, PRPF40A, SF3B1, SF3B3, SNRNP200, PUF6
Protein Size: 462

Molecular Weight: 52 kDa

Gene ID: 2078

NCBI Accession: NM_004449, NP_004440

UniProt: P11308