Paired Box 2 (PAX2) (Middle Region) antibody

Details for Product No. ABIN184322
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Antigen
Synonyms PAX2, XPax-2, XPax2, pax-2, pax2, PAX-2, PAPRS, Opdc, Pax-2, PAXZF-B, cb378, noi, pax-b, pax2.1, pax2a1, pax[zf-b], paxb
Epitope
Middle Region
(13), (7), (3), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Chicken, Human, Mouse (Murine), Rat (Rattus), Xenopus laevis, Zebrafish
(59), (24), (16), (13), (13), (13), (13), (1), (1), (1)
Host
Rabbit
(58), (7), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(4), (4), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (IHC), Western Blotting (WB)
(51), (30), (12), (10), (10), (2), (2), (1), (1), (1)
Pubmed 1 reference available
Quantity 100 µg
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Catalog No. ABIN184322
229.00 $
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Immunogen Synthetic peptide directed towards the middle region of human PAX2
Sequence VSSASNDPVG SYSINGILGI PRSNGEKRKR DEDVSEGSVP NGDSQSGVDS
Cross-Reactivity Chicken, Human, Mouse (Murine), Rat (Rattus)
Predicted Reactivity Bovine : 100 %, Chicken : 100 %, Dog : 100 %, Guinea pig : 100 %, Human : 100 %, Pig : 100 %, Rabbit : 100 %, Sheep : 100 %, Zebrafish : 100 %, African clawed frog : 90 %, Mouse : 90 %, Rat : 90 %
Purification Protein A purified
Alternative Name PAX2
Background PAX2 encodes paired box gene 2, one of many human homologues of the Drosophila melanogaster gene prd. The central feature of this transcription factor gene family is the conserved DNA-binding paired box domain. PAX2 is believed to be a target of transcriptional supression by the tumor supressor gene WT1. Mutations within PAX2 have been shown to result in optic nerve colobomas and renal hypoplasia.
Molecular Weight 45 kDa
NCBI Accession NP_003979, NM_003988
UniProt Q02962
Application Notes WB Suggested Anti-PAX2 Antibody Titration: 1.0 µg/mL
ELISA Titer: 1:312500
Positive Control: Human Liver.
Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 417 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage 4 °C
Storage Comment Any unfrozen and/or unused material can be stored at 4 °C for short term use (< 1 week), and should not be re-frozen. For longer periods of storage, store at -24 °C
Supplier Images
anti-Paired Box 2 (PAX2) (Middle Region) antibody WB Suggested Anti-PAX2 Antibody Titration: 1.0ug/ml
ELISA Titer: 1:312500
Positive Control: Human Liver
Background publications Muratovska, Zhou, He et al.: "Paired-Box genes are frequently expressed in cancer and often required for cancer cell survival." in: Oncogene, Vol. 22, Issue 39, pp. 7989-97, 2003 (PubMed).

Validation Images
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