STAT-Induced STAT Inhibitor 3 (SOCS3) antibody

Antigen: STAT-Induced STAT Inhibitor 3 (SOCS3)

Synonyms: CIS3, SSI3, ATOD4, Cish3, SSI-3, SOCS-3, MGC71791, Cis3, Ef10, Ssi3, EF-10

Clonality: Polyclonal

Host: Goat

Reactivity: Human

Application: ELISA, Western Blotting (WB)

Catalog no.: ABIN184566

Additional Information

Alternative name: SOCS3

Gene ID: 9021, 12702 (mouse), 89829 (rat)

Immunogen: C-PIREFLDQYDAPL

Format: Affinity-purified

Description: All names and symbols: SOCS3, CIS3, Cish3, SSI-3, SOCS-3, suppressor of cytokine signaling 3, STAT induced STAT inhibitor 3, cytokine-induced SH2 protein 3. Official Symbol: SOCS3. RefSeq number(s): NP_003946.3. Gene ontology terms: intracellular signaling cascade, regulation of cell growth

Specificity: Human, Mouse, Rat, Dog, Pig 225 aa

Application Details

Application Notes: Western blot: Approx 24kDa band seen in MOLT-4 lysate. Recommended for use at 4-6µg/ml.

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Buffer: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Storage: Aliquot and store at -20°C. Minimize freezing and thawing.

Research Area: Cancer, Hematopoietic Progenitors, Innate Immunity, Cytokines, Signaling

Restrictions: For Research Use only

Images

ABIN184566 staining (5µg/ml) of MOLT-4 lysate (RIPA buffer, 30µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.

Publications

Publications: Roberts, Robb, Rakar et al.: "Placental defects and embryonic lethality in mice lacking suppressor of cytokine signaling 3." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 16, pp. 9324-9, 2001 (PubMed).