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PDX1 antibody
PDX1
Reactivity: Human
WB, ELISA, FACS
Host: Mouse
Monoclonal
unconjugated
Product Details anti-PDX1 Antibody
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Target
See all PDX1 Antibodies
PDX1
(Pancreatic and Duodenal Homeobox 1 (PDX1))
Reactivity
All reactivities for PDX1 antibodies
Human
Host
All hosts for PDX1 antibodies
Mouse
Clonality
All clonalities for PDX1 antibodies
Monoclonal
Conjugate
All conjugates for PDX1 antibodies
This PDX1 antibody is un-conjugated
Application
All applications for PDX1 antibodies
Western Blotting (WB), ELISA, Flow Cytometry (FACS)
Purification
Purified antibody
Immunogen
Purified recombinant fragment of human PDX1 expressed in E. coli.
Isotype
IgG1
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Discover our top product PDX1 Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1.0 mg/mL
Buffer
PBS with 0.05 % sodium azide and 0.5 % protein stabilizer.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
Target Details for PDX1
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Target
PDX1
(Pancreatic and Duodenal Homeobox 1 (PDX1))
Alternative Name
PDX1 (PDX1 Products )
Synonyms
GSF antibody, IDX-1 antibody, IPF1 antibody, IUF1 antibody, MODY4 antibody, PDX-1 antibody, STF-1 antibody, ipf1 antibody, PDX1 antibody, IPF-1 antibody, Ipf1 antibody, Mody4 antibody, pdx-1 antibody, Idx1 antibody, Stf1 antibody, zgc:100874 antibody, XlHbox-8 antibody, xlhbox8 antibody, pancreatic and duodenal homeobox 1 antibody, pancreatic and duodenal homeobox 1 S homeolog antibody, PDX1 antibody, pdx1 antibody, Pdx1 antibody, pdx1.S antibody
Background
The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2.The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression.Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4).
Molecular Weight
30.8 kDa
Gene ID
3651
UniProt
P52945
Pathways
Nuclear Receptor Transcription Pathway , Positive Regulation of Peptide Hormone Secretion , Steroid Hormone Mediated Signaling Pathway , Hormone Transport , Carbohydrate Homeostasis , Chromatin Binding , Maintenance of Protein Location
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