IL3RA antibody (AA 200-305)

Catalog No. ABIN1845738

Product Details anti-IL3RA Antibody

Target: IL3RA (Interleukin 3 Receptor, alpha (IL3RA))

Binding Specificity: AA 200-305

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This IL3RA antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Immunofluorescence (fixed cells) (IF/ICC)

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human IL3RA (AA: 200-305) expressed in E. coli.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: PBS with 0.05 % sodium azide and 0.5 % protein stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.

Target Details for IL3RA

Target: IL3RA (Interleukin 3 Receptor, alpha (IL3RA))

Alternative Name: IL3RA (IL3RA Products)

Synonyms: CD123 antibody, IL3R antibody, IL3RAY antibody, IL3RX antibody, IL3RY antibody, hIL-3Ra antibody, CDw123 antibody, SUT-1 antibody, Cyrl antibody, interleukin 3 receptor subunit alpha antibody, interleukin 3 receptor, alpha chain antibody, IL3RA antibody, Il3ra antibody

Background: The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor.The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5).The binding of this protein to IL3 depends on the beta subunit.The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3.This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y.Alternatively spliced transcript variants encoding distinct isoforms have been found., , , ,.

Molecular Weight: 43.3 kDa

Gene ID: 3563, 16188

Pathways: JAK-STAT Signaling