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CD59 antibody (AA 31-111)

CD59 Reactivity: Human FACS, WB, IHC, ELISA, IF/ICC Host: Mouse Monoclonal unconjugated
Catalog No. ABIN1845905
  • Target See all CD59 Antibodies
    CD59
    Binding Specificity
    • 16
    • 10
    • 8
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 31-111
    Reactivity
    • 137
    • 14
    • 9
    • 8
    • 5
    • 3
    • 2
    • 1
    • 1
    Human
    Host
    • 89
    • 69
    • 6
    • 4
    Mouse
    Clonality
    • 96
    • 69
    • 1
    Monoclonal
    Conjugate
    • 77
    • 21
    • 16
    • 13
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD59 antibody is un-conjugated
    Application
    • 100
    • 69
    • 45
    • 40
    • 30
    • 28
    • 25
    • 15
    • 15
    • 14
    • 13
    • 12
    • 11
    • 11
    • 7
    • 3
    • 3
    • 3
    • 1
    • 1
    Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (fixed cells) (IF/ICC)
    Purification
    Purified antibody
    Immunogen
    Purified recombinant fragment of human CD59 (AA: 31-111) expressed in E. Coli.
    Isotype
    IgG1
    Top Product
    Discover our top product CD59 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1.0 mg/mL
    Buffer
    PBS with 0.05 % sodium azide and 0.5 % protein stabilizer.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
  • Target
    CD59
    Alternative Name
    CD59 (CD59 Products)
    Synonyms
    16.3A5 antibody, 1F5 antibody, EJ16 antibody, EJ30 antibody, EL32 antibody, G344 antibody, HRF-20 antibody, HRF20 antibody, MAC-IP antibody, MACIF antibody, MEM43 antibody, MIC11 antibody, MIN1 antibody, MIN2 antibody, MIN3 antibody, MIRL antibody, MSK21 antibody, p18-20 antibody, Cd59a antibody, Cd59b antibody, MACIP antibody, CD59 molecule (CD59 blood group) antibody, CD59 molecule antibody, CD59 antibody, Cd59 antibody
    Background
    This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation.
    Molecular Weight
    14.2 kDa
    Gene ID
    966
    UniProt
    P13987
    Pathways
    Complement System
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