STAT3 antibody (Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor)) (C-Term)

Details for Product anti-STAT3 Antibody No. ABIN184593, Supplier: Log in to see
Antigen
  • 1110034C02Rik
  • AW109958
  • Aprf
  • APRF
  • HIES
  • Xstat3
  • aprf
  • hies
  • stat3
  • wu:fc15d02
  • wu:fl59g06
  • z-Stat3
  • signal transducer and activator of transcription 3 (acute-phase response factor)
  • signal transduction and activation of transcription 3
  • signal transducer and activator of transcription 3
  • signal transducer and activator of transcription 3 (acute-phase response factor), gene 1
  • STAT3
  • stat3
  • Stat3
  • stat3.1
Alternatives
anti-Human STAT3 antibody for Immunofluorescence (fixed cells)
Epitope
C-Term
113
89
71
25
18
17
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16
16
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13
11
6
5
5
5
5
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4
4
4
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
589
344
272
40
37
33
29
16
11
10
7
5
5
5
4
3
3
2
1
1
1
1
1
Host
Goat
459
136
33
5
2
1
Clonality
Polyclonal
Conjugate
This STAT3 antibody is un-conjugated
28
23
18
14
11
11
9
6
4
4
4
2
2
2
2
2
2
2
2
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2
1
1
1
1
1
Method Type
Peptide ELISA
Application
Immunohistochemistry (IHC), ELISA
541
242
215
92
81
80
58
54
27
12
11
9
8
6
5
3
3
3
2
2
2
2
1
1
1
1
Options
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Immunogen Peptide with sequence DMELTSECATSPM, from the C Terminus of the protein sequence according to NP_003141.2, NP_644805.1.
Blocking Peptide Blocking peptide for this product available: ABIN370087
Specificity This antibody is expected to recognise isoforms 1 and 2 (as represented by NP_644805.1 and NP_003141.2 respectively)
Cross-Reactivity Dog (Canine), Pig (Porcine), Cow (Bovine)
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Alternative Name STAT3 (STAT3 Antibody Abstract)
Background Synonyms: STAT3, signal transducer and activator of transcription 3 (acute-phase response factor), APRF, DNA-binding protein APRF, acute-phase response factor, FLJ20882, MGC16063, HIES
Gene ID 6774, 20848, 25125
NCBI Accession NP_003141, NP_644805
Pathways JAK-STAT Signaling, RTK Signaling, Interferon-gamma Pathway, Neurotrophin Signaling Pathway, Dopaminergic Neurogenesis, Response to Growth Hormone Stimulus, Carbohydrate Homeostasis, Stem Cell Maintenance, Hepatitis C, Protein targeting to Nucleus, Feeding Behaviour, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor
Application Notes ELISA: antibody detection limit dilution 1:4000.
IHC: In paraffin embedded Mouse Thymus shows preferential staining of the medula over the cortex. Recommended concentration: 4-8 µg/mL. Immunofluorescence: An anonymous customer found positive results in IF on Human HEK 293 cells. IF, An anonymous customer found positive results in IF on Rat glial processes and nuclei.
Restrictions For Research Use only
Format Liquid
Buffer Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Minimize freezing and thawing.
Storage -20 °C
Storage Comment Aliquot and store at -20 °C.
Supplier Images
 image for anti-STAT3 antibody (Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor)) (C-Term) (ABIN184593) ABIN184593 (1µg/ml) staining of NIH3T3 lysate (35µg protein in RIPA buffer). Primary ...
Immunohistochemistry (IHC) image for anti-STAT3 antibody (Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor)) (C-Term) (ABIN184593) ABIN184593 overnight staining at 10ug/ml on 4%PFA-fixed mouse thymus. Biotinylated mo...
Background publications Bromberg, Wrzeszczynska, Devgan, Zhao, Pestell, Albanese, Darnell: "Stat3 as an oncogene." in: Cell, Vol. 98, Issue 3, pp. 295-303, 1999 (PubMed).