Prostaglandin-Endoperoxide Synthase 1 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS1) antibody

Antigen: Prostaglandin-Endoperoxide Synthase 1 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS1)

Synonyms: COX1, COX3, PHS1, PCOX1, PGHS1, PTGHS, PGG/HS, PGHS-1, Cox-1, Cox-3, Pghs1, Cox1, Cox3, PTGS1, COX-1, Ptgs1, cox1, cox-1, zCOX-1, COX-3

Clonality: Polyclonal

Host: Goat

Reactivity: Human

Application: ELISA, Western Blotting (WB)

Catalog no.: ABIN184671

Additional Information

Alternative name: COX1 / PTGS1

Gene ID: 5742

Immunogen: C-QDDGPAVERPSTEL

Format: Ig-fraction

Description: All names and symbols: PTGS1, COX1, COX3, PHS1, PCOX1, PGHS1, PTGHS, PGG/HS, PGHS-1, prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase), prostaglandin G/H synthase and cyclooxygenase. Official Symbol: PTGS1. RefSeq number(s): NP_000953.2, NP_542158.1. Gene ontology terms: prostaglandin-endoperoxide synthase activity, peroxidase activity, physiological processes, lipid metabolism, membrane, prostaglandin biosynthesis, oxidoreductase activity, oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen

Specificity: This antibody is expected to recognise both human isoforms of this protein according to NP_000953.2 and NP_542158.1. Human 599 aa, 562 aa

Application Details

Application Notes: Western blot: Approx 65-70kDa bands seen in HeLa lysate. Recommended for use at 1-3µg/ml.

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Buffer: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Storage: Aliquot and store at -20°C. Minimize freezing and thawing.

Restrictions: For Research Use only

Images

ABIN184671 staining (1µg/ml) of HeLa lysate (RIPA buffer, 30µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.

Publications

Publications: Yokoyama, Tanabe: "Cloning of human gene encoding prostaglandin endoperoxide synthase and primary structure of the enzyme." in: Biochemical and biophysical research communications, Vol. 165, Issue 2, pp. 888-94, 1990 (PubMed).