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Amyotrophic Lateral Sclerosis 2 (Juvenile) (ALS2) (C-Term) antibody

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Synonyms als2, si:dkey-33m14.1, ALS2CR6, ALSJ, IAHSP, PLSJ, 3222402C23Rik, 9430073A21Rik, Als2cr6, Alsin, mKIAA1563
(23), (5), (4), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1)
(71), (29), (27), (4), (4), (1), (1), (1), (1)
(47), (19), (9)
(2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Methode Type Peptide ELISA
Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
(46), (32), (25), (12), (11), (3), (2), (1)
Pubmed 1 reference available
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Quantity 100 μg
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Availability Available
Immunogen Peptide with sequence LKACYYQIQREKLN, from the C Terminus of the protein sequence according to NP_065970.2.
Blocking Peptide Blocking peptide for this product available: ABIN370347
Cross-Reactivity Mouse (Murine), Rat (Rattus), Dog (Canine), Cow (Bovine)
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Alternative Name Alsin / ALS2 (ALS2 Antibody Abstract)
Background Synonyms: ALS2, amyotrophic lateral sclerosis 2 (juvenile), ALSJ, PLSJ, IAHSP, KIAA1563, ALS2CR6, FLJ31851, MGC87187, alsin
Gene ID 57679
NCBI Accession NP_065970
Application Notes ELISA: antibody detection limit dilution 1:8000.
Western blot: No signal obtained yet but low background observed in Human Brain extracts at upto 1 µg/mL.
IHC: In paraffin embedded Human Cortex shows pixulate cytoplasm staining in some neuronal cells. Recommended concentration: 3-5 µg/mL.
Restrictions For Research Use only
Format Liquid
Concentration 100µg specific antibody in 200µl
Buffer Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Minimize freezing and thawing.
Storage -20 °C
Storage Comment Aliquot and store at -20 °C.
Background publications Yang, Hentati, Deng et al.: "The gene encoding alsin, a protein with three guanine-nucleotide exchange factor domains, is mutated in a form of recessive amyotrophic lateral sclerosis." in: Nature genetics, Vol. 29, Issue 2, pp. 160-5, 2001 (PubMed).

Catalog No. ABIN184691
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