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Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1) antibody

Details for Product No. ABIN184837, Supplier: Login to see New
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(142), (53), (37), (3), (2), (2), (1), (1), (1), (1), (1)
(111), (31), (15), (2)
(9), (5), (5), (5), (5), (5), (2), (2), (2), (2), (2), (2), (2), (2), (2)
(130), (85), (22), (21), (14), (14), (11), (5), (4), (4), (4), (1), (1)
Pubmed 1 reference available
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Quantity 100 μg
Shipping to United States ( )
Blocking Peptide Blocking peptide for this product available: ABIN369569
Specificity Human 977 aa
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Alternative Name IRE1 / ERN1 (ERN1 Antibody Abstract)
Background All names and symbols: ERN1, endoplasmic reticulum to nucleus signalling 1, FLJ30999, IRE1, IRE1P, MGC163277, MGC163279, ER to nucleus signalling 1, inositol-requiring 1, protein kinase/endoribonuclease. Official Symbol: ERN1. RefSeq number(s): NP_001424.3. Gene ontology terms: endoribonuclease activity, ATP binding, protein serine/threonine kinase activity, DNA binding, electron transport, protein amino acid phosphorylation, endoplasmic reticulum membrane, nucleus, transferase activity
Gene ID 2081
Application Notes Peptide ELISA: antibody detection limit dilution 1:4,000. Western Blot: No signal obtained yet but low background observed in HepG2 lysates at up to 2µg/ml. We would appreciate any feedback from people in the field - have any results been reported with other antibodies/lysates?
Restrictions For Research Use only
Format Liquid
Buffer 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
General Tirasophon, Welihinda, Kaufman: "A stress response pathway from the endoplasmic reticulum to the nucleus requires a novel bifunctional protein kinase/endoribonuclease (Ire1p) in mammalian cells." in: Genes & development, Vol. 12, Issue 12, pp. 1812-24, 1998 (PubMed).

Catalog No. ABIN184837

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