Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1) antibody

Details for Product No. ABIN184837
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Antigen
Synonyms 9030414B18Rik, AI225830, C85377, Ire1a, Ire1alpha, Ire1p, RGD1559716, IRE1, IRE1P, IRE1a, hIRE1p
Reactivity
Human
(99), (49), (48), (25), (24), (24)
Host
Goat
(78), (23), (6)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application
ELISA
(88), (54), (24), (20), (16), (9), (6), (2), (2), (1), (1)
Pubmed 1 reference available
Catalog no. ABIN184837
Quantity 100 µg
Price
261.61 $   Plus shipping costs $45.00
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Immunogen C-PPEPQPPVTPDAL
Specificity Human 977 aa
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Alternative Name IRE1 / ERN1
Background All names and symbols: ERN1, endoplasmic reticulum to nucleus signalling 1, FLJ30999, IRE1, IRE1P, MGC163277, MGC163279, ER to nucleus signalling 1, inositol-requiring 1, protein kinase/endoribonuclease. Official Symbol: ERN1. RefSeq number(s): NP_001424.3. Gene ontology terms: endoribonuclease activity, ATP binding, protein serine/threonine kinase activity, DNA binding, electron transport, protein amino acid phosphorylation, endoplasmic reticulum membrane, nucleus, transferase activity
Gene ID 2081
Application Notes Peptide ELISA: antibody detection limit dilution 1:4,000. Western Blot: No signal obtained yet but low background observed in HepG2 lysates at up to 2µg/ml. We would appreciate any feedback from people in the field - have any results been reported with other antibodies/lysates?
Restrictions For Research Use only
Format Liquid
Buffer 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Preservative Sodium azide
Storage -20 °C
General Tirasophon, Welihinda, Kaufman: "A stress response pathway from the endoplasmic reticulum to the nucleus requires a novel bifunctional protein kinase/endoribonuclease (Ire1p) in mammalian cells." in: Genes & development, Vol. 12, Issue 12, pp. 1812-24, 1998 (PubMed).

Hosts (78), (23), (6)
Reactivities (99), (49), (48), (25), (24), (24)
Applications (88), (54), (24), (20), (16), (9), (6), (2), (2), (1), (1)
Conjugates (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Epitopes (16), (12), (10), (9), (7), (4), (4), (2), (2), (1), (1), (1), (1), (1), (1)
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