CAP-GLY Domain Containing Linker Protein 2 (CLIP2) antibody

Antigen: CAP-GLY Domain Containing Linker Protein 2 (CLIP2)

Synonyms: CLIP, CYLN2, WSCR3, WSCR4, WBSCR3, WBSCR4, CLIP-115, KIAA0291, MGC11333, Cyln2, Clip1, wbscr4, mKIAA0291, B230327O20

Clonality: Polyclonal

Host: Goat

Reactivity: Please enquire

Conjugate: Un-conjugated

Application: ELISA

Catalog no.: ABIN184849

Additional Information

Alternative name: CYLN2

Gene ID: 7461

Immunogen: C-HQQDKAQKQEDKH

Description: All names and symbols: CYLN2, cytoplasmic linker 2, WSCR4, WBSCR4, CLIP-115, KIAA0291, MGC11333, Williams-Beuren syndrome chromosome region 4. Official Symbol: CYLN2. RefSeq number(s): NP_003379, NP_115797. Gene ontology terms: microtubule associated protein

Specificity: This antibody is expected to recognise both human isoforms of this protein, as represented by NP_003379 and NP_115797. Human

Application Details

Application Notes: Peptide ELISA: antibody detection limit dilution >1:32,000. Western Blot: Preliminary experiments gave 3 bands at approx 150kDa, 125kDa and 100kDa in human brain lysates at 0.1ug/ml. Please note that currently we cannot find an explanation in the literature for the bands we observe given the predicted size of approx. 120kDda and 116kDa according to NP_003379 and NP_115797. We would appreciate any feedback from people in the field - have any results been reported with other antibodies/lysates? Have any further splice variants/modified forms been reported?

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Buffer: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Storage: Aliquot and store at -20°C. Minimize freezing and thawing.

Research Area: Neurology

Restrictions: For Research Use only

Publications

Osborne, Martindale, Scherer et al.: "Identification of genes from a 500-kb region at 7q11.23 that is commonly deleted in Williams syndrome patients." in: Genomics, Vol. 36, Issue 2, pp. 328-36, 1997 (PubMed).

Hoogenraad, Eussen, Langeveld et al.: "The murine CYLN2 gene: genomic organization, chromosome localization, and comparison to the human gene that is located within the 7q11.23 Williams syndrome critical region." in: Genomics, Vol. 53, Issue 3, pp. 348-58, 1998 (PubMed).