Wolf-Hirschhorn Syndrome Candidate 1 (WHSC1) antibody

Antigen: Wolf-Hirschhorn Syndrome Candidate 1 (WHSC1)

Synonyms: WHS, NSD2, TRX5, MMSET, REIIBP, FLJ23286, KIAA1090, MGC176638, Whsc1l, AW555663, mKIAA1090, 5830445G22Rik, 9430010A17Rik, C130020C13Rik, D030027O06Rik, D930023B08Rik, WHSC1, RGD1565590, fc12c04, wu:fc12c04, wu:fi20c01, si:rp71-77d7.2, whs, nsd2, trx5, mmset, reiibp

Clonality: Polyclonal

Host: Goat

Reactivity: Please enquire

Application: ELISA

Catalog no.: ABIN184883

Additional Information

Alternative name: WHSC1 / MMSET

Gene ID: 7468

Immunogen: EFSIKQSPLSVQS-C

Description: All names and symbols: WHSC1, Wolf-Hirschhorn syndrome candidate 1, NSD2, TRX5, MMSET, REIIBP, KIAA1090, trithorax/ash1-related protein 5, multiple myeloma SET domain protein, IL-5 promoter REII-region-binding protein. Official Symbol: WHSC1. RefSeq number(s): NP_015627, NP_055734, NP_579877, NP_579878, NP_579879, NP_579888, NP_579889, NP_579890. Gene ontology terms: oncogenesis, embryogenesis and morphogenesis

Specificity: This antibody is expected to recognise eight of the nine reported human isoforms of this protein (isoform 5 (NP_579891) has a distinct N terminus). Human 629 aa, 802 aa, 1365 aa, 1365 aa, 647 aa, 647 aa, 647 aa, 1365 aa

Synonyms: WHS, NSD2, TRX5, MMSET, REIIBP, FLJ23286, KIAA1090, MGC176638, Whsc1l, AW555663, mKIAA1090, 5830445G22Rik, 9430010A17Rik, C130020C13Rik, D030027O06Rik, D930023B08Rik, WHSC1, RGD1565590, fc12c04, wu:fc12c04, wu:fi20c01, si:rp71-77d7.2, whs, nsd2, trx5, mmset, reiibp

Application Details

Application Notes: Peptide ELISA: antibody detection limit dilution 1:64,000. Western Blot: Preliminary experiments gave an approx 65kDa band in human liver and 293 lysates at 1ug/ml, this was always accompanied by a much stronger band at 25-30kDa. Please note that current

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Buffer: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Storage: Aliquot and store at -20°C. Minimize freezing and thawing.

Restrictions: For Research Use only

Publications

Stec, Wright, van Ommen et al.: "WHSC1, a 90 kb SET domain-containing gene, expressed in early development and homologous to a Drosophila dysmorphy gene maps in the Wolf-Hirschhorn syndrome critical region and is fused to IgH in t(4;14) multiple myeloma." in: Human molecular genetics, Vol. 7, Issue 7, pp. 1071-82, 1999 (PubMed).