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Chromobox Homolog 6/8 (CBX6/8) (N-Term) antibody

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Synonyms cbx6, CBX6
Human, Mouse (Murine), Rat (Rattus), Dog (Canine), Pig (Porcine), Cow (Bovine)
(1), (1), (1), (1), (1), (1)
Methode Type Peptide ELISA
ELISA, Western Blotting (WB)
Pubmed 1 reference available
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Quantity 100 μg
Shipping to United States ( )
Availability Available
Immunogen Peptide with sequence ELSAVGERVFAAE-C, from the N Terminus of the protein sequence according to NP_055107.3, NP_065700.1.
Blocking Peptide Blocking peptide for this product available: ABIN370123
Specificity This antibody is expected to recognise both the human proteins CBX6 and CBX8, which are almost identical.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Alternative Name CBX6 and CBX8
Background Synonyms: CBX6, chromobox homolog 6, CBX8, chromobox homolog 8, PC3, RC1, HPC3, polycomb 3, Neuronal pentraxin receptor, chromobox homolog 8 (Pc class homolog, Drosophila)
Gene ID 23466, 57332
NCBI Accession NP_065700, NP_055107
Application Notes ELISA: antibody detection limit dilution 1:64000.
Western blot: Preliminary experiments gave an approx 37 kDa band in Human, Mouse and Rat Brain lysates at 0.3 µg/mL. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 43.8 kDa according to NP_055107.3 (CBX6) and 43.4 kDa according to NP_065700.1 (CBX8).
Restrictions For Research Use only
Format Liquid
Buffer Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Minimize freezing and thawing.
Storage -20 °C
Storage Comment Aliquot and store at -20 °C.
Background publications Bárdos, Saurin, Tissot et al.: "HPC3 is a new human polycomb orthologue that interacts and associates with RING1 and Bmi1 and has transcriptional repression properties." in: The Journal of biological chemistry, Vol. 275, Issue 37, pp. 28785-92, 2000 (PubMed).

Catalog No. ABIN184901
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