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Activin A Receptor Type II-Like 1 (ACVRL1) (C-Term) antibody

Details for Product No. ABIN185181, Supplier: Log in to see
Antigen
  • ACVRL1
  • vgb
  • alk1
  • zehn1109
  • hm:zehn1109
  • ACVRLK1
  • ALK-1
  • ALK1
  • HHT
  • HHT2
  • ORW2
  • SKR3
  • TSR-I
  • R-3
  • R3
  • SETHKIR
  • AI115505
  • AI427544
  • Acvrlk1
  • Alk1
Epitope
C-Term
35
24
13
11
10
6
6
5
4
2
2
2
2
1
1
1
1
Reactivity
Human
123
35
27
3
2
2
Host
Goat
93
15
15
1
Clonality
Polyclonal
Conjugate
Un-conjugated
6
6
6
5
5
5
1
1
1
1
1
1
1
1
1
Methode Type
Peptide ELISA
Application
ELISA, Western Blotting (WB)
98
68
47
21
21
11
9
5
2
1
1
1
Supplier
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Immunogen Peptide with sequence C-KISNSPEKPKVIQ, from the C Terminus of the protein sequence according to NP_000011.2, NP_001070869.1.
Blocking Peptide Blocking peptide for this product available: ABIN369289
Specificity Please note that this product is not to be confused with the similarly named ALK (anaplastic lymphoma kinase, GeneID 238). Reported variant represent identical protein: NP_000011.2, NP_001070869.1
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Alternative Name Activin receptor-like kinase 1 (ACVRL1 Antibody Abstract)
Background Synonyms: ACVRL1, HHT, ALK1, HHT2, ORW2, SKR3, ALK-1, ACVRLK1, activin A receptor type II-like 1, Activin A receptor, type II-like kinase 1, ALK1, TSR-I, TGF-B superfamily receptor type I, activin A receptor, type II-like kinase 1, serine/threonine-protein kinase receptor R3
Gene ID 94
NCBI Accession NP_001070869, NP_000011
Pathways
Application Notes ELISA: antibody detection limit dilution 1:32000.
Western blot: Approx 60 kDa band observed in lysates of cell line MCF7 (calculated MW of 56.1 kDa according to NP_000011.2). Recommended concentration: 1-3 µg/mL.
Restrictions For Research Use only
Format Liquid
Buffer Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Minimize freezing and thawing.
Storage -20 °C
Storage Comment Aliquot and store at -20 °C.
Background publications Johnson, Berg, Baldwin et al.: "Mutations in the activin receptor-like kinase 1 gene in hereditary haemorrhagic telangiectasia type 2." in: Nature genetics, Vol. 13, Issue 2, pp. 189-95, 1996 (PubMed).