Exoribonuclease 1 (ERI1) antibody

Antigen: Exoribonuclease 1 (ERI1)

Synonyms: HEXO, THEX1, 3'HEXO, MGC35395, Thex1, MGC108797, RGD1308378, ERI1, Eri-1, MGC134299, thex1, MGC110635, zgc:110635, eri-1, 3'hexo, 3110010F15Rik

Clonality: Polyclonal

Host: Goat

Reactivity: Please enquire

Application: ELISA

Catalog no.: ABIN185245

Additional Information

Alternative name: 3'hExo / THEX1

Gene ID: 90459

Immunogen: EDPQSKEPAGEA-C

Description: All names and symbols: 3'HEXO, MGC35395, 3' exoribonuclease, 3'-5' exonuclease ERI1, THEX1, three prime histone mRNA exonuclease 1. Official Symbol: THEX1. RefSeq number(s): NP_699163. Gene ontology terms: exonuclease activity, DNA binding, nucleus

Specificity: Human

Application Details

Application Notes: Peptide ELISA: antibody detection limit dilution 1:4,000. Western Blot: Preliminary experiments gave no signal but low background in Human Brain and Liver lysates at up to 1µg/ml. We would appreciate any feedback from people in the field - have any results been reported with other antibodies/lysates?

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Buffer: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Storage: Aliquot and store at -20°C. Minimize freezing and thawing.

Restrictions: For Research Use only

Publications

Dominski, Yang, Kaygun et al.: "A 3' exonuclease that specifically interacts with the 3' end of histone mRNA." in: Molecular cell, Vol. 12, Issue 2, pp. 295-305, 2003 (PubMed).