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Cannabinoid Receptor 1 (CNR1) (Internal Region) antibody

Details for Product No. ABIN185484
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Antigen
Synonyms CNR1, LOC540382, CB1, CNR, CB-R, CB1A, CB1R, CANN6, CB1K5, SKR6R, cnr1-A
Epitope
Internal Region
(10), (10), (9), (7), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine)
(76), (40), (34), (15), (12), (12), (12), (4), (1), (1), (1), (1), (1)
Host
Goat
(67), (8), (6)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Methode Type Peptide ELISA
Application
ELISA, Western Blotting (WB)
(62), (36), (21), (14), (10), (9), (9), (4), (1), (1), (1), (1), (1)
Pubmed 1 reference available
Quantity 100 µg
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Availability Available
Catalog No. ABIN185484
374.27 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen Peptide with sequence C-HTSEDGKVQVTRPDQ, from the internal region of the protein sequence according to NP_057167.2, NP_001153732.1, NP_001153731.1, NP_001153730.1, NP_001153698.1, NP_149421.1.
Specificity This antibody is expected to recognise both reported isoforms. Isoform a (NP_057167.2, NP_001153732.1, NP_001153731.1, NP_001153730.1, NP_001153698.1) and isoform b (NP_149421.1).
Cross-Reactivity Rat (Rattus), Dog (Canine)
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Alternative Name Cannabinoid Receptor 1
Background Synonyms: cannabinoid receptor 1 (brain), CNR1, HGNC:2159, CANN6, CB-R, CB1, CB1A, CB1K5, CNR, central cannabinoid receptor, RP1-23D17.1, CB1R, OTTHUMP00000016838, OTTHUMP00000016839, cannabinoid receptor 1
Gene ID 1268, 12801, 25248
NCBI Accession NP_057167.2, NP_001153732.1, NP_001153731.1, NP_001153730.1, NP_001153698.1, NP_149421.1
Application Notes ELISA: antibody detection limit dilution 1:32000.
Western blot: Approx 65 kDa band observed in Rat Brain lysates (calculated MW of 52.7 kDa according to Rat NP_036916.1 and 52.9 kDa according to Human NP_057167.2). The observed molecular weight corresponds to earlier findings in literature with different antibodies (Porcella et al, Eur J Neurosci. 2000 Mar,12(3):1123-7. PMID: 10762343). Recommended concentration: 0.1-0.3 µg/mL.
Restrictions For Research Use only
Format Liquid
Buffer Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Minimize freezing and thawing.
Storage -20 °C
Storage Comment Aliquot and store at -20 °C.
Supplier Images
anti-Cannabinoid Receptor 1 (CNR1) (Internal Region) antibody ABIN185484 (1µg/ml) staining of human brain lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
General Ledent, Valverde, Cossu et al.: "Unresponsiveness to cannabinoids and reduced addictive effects of opiates in CB1 receptor knockout mice." in: Science (New York, N.Y.), Vol. 283, Issue 5400, pp. 401-4, 1999 (PubMed).

Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN185484
374.27 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
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