Cannabinoid Receptor 1 (CNR1) (Internal Region) antibody

Details for Product No. ABIN185484
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Antigen
Synonyms CB1, CNR, CB-R, CB1A, CB1R, CANN6, CB1K5, SKR6R, CNR1, LOC540382
Epitope
Internal Region
(10), (7), (4), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine)
(72), (42), (34), (15), (12), (12), (12), (4), (1), (1), (1), (1), (1)
Host
Goat
(63), (8), (8)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Methode Type Peptide ELISA
Application
ELISA, Western Blotting (WB)
(60), (34), (25), (18), (10), (9), (9), (4), (4), (1), (1), (1), (1), (1)
Pubmed 1 reference available
Catalog no. ABIN185484
Quantity 100 µg
Price
374.27 $   Plus shipping costs $45.00
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Immunogen Peptide with sequence C-HTSEDGKVQVTRPDQ, from the internal region of the protein sequence according to NP_057167.2, NP_001153732.1, NP_001153731.1, NP_001153730.1, NP_001153698.1, NP_149421.1.
Specificity This antibody is expected to recognise both reported isoforms. Isoform a (NP_057167.2, NP_001153732.1, NP_001153731.1, NP_001153730.1, NP_001153698.1) and isoform b (NP_149421.1).
Cross-Reactivity Rat (Rattus), Dog (Canine)
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Alternative Name Cannabinoid Receptor 1
Background Synonyms: cannabinoid receptor 1 (brain), CNR1, HGNC:2159, CANN6, CB-R, CB1, CB1A, CB1K5, CNR, central cannabinoid receptor, RP1-23D17.1, CB1R, OTTHUMP00000016838, OTTHUMP00000016839, cannabinoid receptor 1
Gene ID 1268, 12801, 25248
NCBI Accession NP_057167.2, NP_001153732.1, NP_001153731.1, NP_001153730.1, NP_001153698.1, NP_149421.1
Application Notes ELISA: antibody detection limit dilution 1:32000.
Western blot: Approx 65 kDa band observed in Rat Brain lysates (calculated MW of 52.7 kDa according to Rat NP_036916.1 and 52.9 kDa according to Human NP_057167.2). The observed molecular weight corresponds to earlier findings in literature with different antibodies (Porcella et al, Eur J Neurosci. 2000 Mar,12(3):1123-7. PMID: 10762343). Recommended concentration: 0.1-0.3 µg/mL.
Restrictions For Research Use only
Format Liquid
Buffer Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
Preservative Sodium azide
Handling Advice Minimize freezing and thawing.
Storage -20 °C
Storage Comment Aliquot and store at -20 °C.
Supplier Images
anti-Cannabinoid Receptor 1 (CNR1) (Internal Region) antibody ABIN185484 (1µg/ml) staining of human brain lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
General Ledent, Valverde, Cossu et al.: "Unresponsiveness to cannabinoids and reduced addictive effects of opiates in CB1 receptor knockout mice." in: Science (New York, N.Y.), Vol. 283, Issue 5400, pp. 401-4, 1999 (PubMed).

Hosts (63), (8), (8)
Reactivities (72), (42), (34), (15), (12), (12), (12), (4), (1), (1), (1), (1), (1)
Applications (60), (34), (25), (18), (10), (9), (9), (4), (4), (1), (1), (1), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (10), (7), (4), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
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