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Details for Product No. ABIN185498

Sirtuin 3 (SIRT3) (C-Term) antibody

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Antigen
Synonyms SIR2L3, zgc:158774, 2310003L23Rik, AI848213, Sir2l3, sirtuin
Epitope
»Alternatives C-Term
Reactivity
»Alternatives Human
Host
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Methode Type Peptide ELISA
Application
»Alternatives ELISA, Western Blotting (WB)
Pubmed 1 reference available
Catalog no. ABIN185498
Quantity 100 µg
Price
374.27 $   Plus shipping costs $45.00
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Availability Ships within 5 Business Days
Immunogen Peptide with sequence C-QRETGKLDGPDK, from the C Terminus of the protein sequence according to NP_036371.1, NP_001017524.1.
Specificity This antibody is expected to recognize both reported isoforms (NP_036371.1 and NP_001017524.1).
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Alternative Name SIRT3
Background Synonyms: SIRT3, sirtuin (silent mating type information regulation 2 homolog) 3 (S. cerevisiae), HGNC:14931, SIR2L3, mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase, silent mating type information regulation 2, S.cerevisiae, homolog 3, sir2-like 3, sirtuin (silent mating type information regulation 2, S.cerevisiae, homolog) 3, sirtuin 3, sirtuin type 3
Gene ID 23410
NCBI Accession NP_036371.1, NP_001017524.1
Research Area Cancer, Proteases
Application Notes ELISA: antibody detection limit dilution 1:128000.
Western blot: Approx 28 kDa band observed in Human Liver lysates (calculated MW of 28.6 kDa according to NP_001017524.1). In transfected HEK293 transiently expressing SIRT3 bands of approx. 35 kDa and 48 kDa are observed. These bands are not observed in the non-transfected HEK293. Recommended concentration: 0.1-0.3 µg/mL.
Restrictions For Research Use only
Format Liquid
Buffer Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
Preservative Sodium azide
Handling Advice Minimize freezing and thawing.
Storage -20 °C
Storage Comment Aliquot and store at -20 °C.
Shi, Wang, Stieren et al.: "SIRT3, a mitochondrial sirtuin deacetylase, regulates mitochondrial function and thermogenesis in brown adipocytes." in: The Journal of biological chemistry, Vol. 280, Issue 14, pp. 13560-7, 2005 (PubMed).

Alternatives for antigen "Sirtuin 3 (SIRT3)", type "Antibodies"
Hosts (62), (9), (7), (4)
Reactivities (69), (33), (25), (14), (12), (3), (2), (1), (1), (1), (1), (1), (1)
Applications (68), (41), (13), (11), (10), (7), (4), (3), (2), (1), (1)
Conjugates (6), (4), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (20), (6), (5), (4), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
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