SH2 Domain Containing 1A (SH2D1A) (Internal Region) antibody

Details for Product No. ABIN185514, Supplier: Log in to see
Antigen
  • DSHP
  • EBVS
  • IMD5
  • LYP
  • MTCP1
  • SAP
  • SAP/SH2D1A
  • XLP
  • XLPD
  • RGD1562408
  • Gm686
  • SH2D1A
  • SH2 domain containing 1A
  • SH2 domain protein 1A
  • SH21A
  • SH2D1A
  • Sh2d1a
  • LOC780420
Alternatives
anti-Human SH2 Domain Containing 1A antibody for ELISA
Epitope
Internal Region
18
17
15
9
8
5
4
3
2
1
1
1
1
1
1
Reactivity
Human
114
39
34
7
7
5
2
2
1
1
1
Host
Goat
72
32
14
1
Clonality
Polyclonal
Conjugate
Un-conjugated
7
7
6
5
5
5
1
1
1
1
1
1
1
1
1
1
1
Method Type
Peptide ELISA
Application
ELISA, Western Blotting (WB)
100
59
13
11
5
4
4
2
1
Options
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Immunogen Peptide with sequence C-QYPVEKKSSARSTQ, from the internal region of the protein sequence according to NP_002342.1, NP_001108409.1.
Blocking Peptide Blocking peptide for this product available: ABIN369733
Cross-Reactivity Pig (Porcine)
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Alternative Name SH2D1A/SLAM associated protein (SH2D1A Antibody Abstract)
Background Synonyms: SH2D1A, SH2 domain protein 1A, DuncanɈdisease (lymphoproliferative syndrome), HGNC:10820, DSHP, EBVS, IMD5, LYP, MTCP1, SAP, XLP, XLPD, SH2 domain protein 1A, SLAM (signaling lymphocyte activation molecule) associated protein, T cell signal transduction molecule SAP, RP5-1052M9.3, FLJ18687, FLJ92177, Duncan's disease (lymphoproliferative syndrome), Duncan's disease, SLAM-associated protein, T cell signal transduction molecule SAP, signaling lymphocyte activation molecule-associated protein
Gene ID 4068
NCBI Accession NP_001108409, NP_002342
Pathways Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
Application Notes ELISA: antibody detection limit dilution 1:32000.
Western blot: Approx 16 kDa band observed in Human Lymph Node lysates (calculated MW of 14.2 kDa according to NP_002342.1). In transfected HEK293 transiently expressing SH2D1A a band of approx. 17 kDa is observed. This band is not observed in the non-transfected HEK293. Recommended concentration: 0.2-0.6 µg/mL.
Restrictions For Research Use only
Format Liquid
Buffer Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Minimize freezing and thawing.
Storage -20 °C
Storage Comment Aliquot and store at -20 °C.
Supplier Images
 image for anti-SH2 Domain Containing 1A (SH2D1A) (Internal Region) antibody (ABIN185514) ABIN185514 (0.2µg/ml) staining of human lymph node lysate (35µg protein in RIPA buffe...
Background publications Romero, Benítez, March, Vilella, Miralpeix, Engel: "Differential expression of SAP and EAT-2-binding leukocyte cell-surface molecules CD84, CD150 (SLAM), CD229 (Ly9) and CD244 (2B4)." in: Tissue antigens, Vol. 64, Issue 2, pp. 132-44, 2004 (PubMed).