HGS antibody (Internal Region)

Catalog No. ABIN185612

Product Details anti-HGS Antibody

Target: HGS (Hepatocyte Growth Factor-Regulated tyrosine Kinase Substrate (HGS))

Binding Specificity: Internal Region

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This HGS antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purpose: HRS / HGS

Sequence: NRNYWEKKQE EARK

Cross-Reactivity: Dog, Human, Mouse, Rat

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Grade: Verified

Immunogen: Peptide with sequence C-NRNYWEKKQEEARK, from the internal region of the protein sequence according to NP_004703.1.

Isotype: IgG

Application Details

Application Notes:

Immunohistochemistry: In paraffin embedded Human Testis shows strong staining of Leydig cells. Recommended concentration: 1-2 μg/mL.

Western Blot: This antibody has been successfully used in Western Blot on Human: Clancy et al. (2020) https://doi.org/10.1101/2020.04.15.042291.

Peptide ELISA: antibody detection limit dilution 1:32000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

Target Details for HGS

Target: HGS (Hepatocyte Growth Factor-Regulated tyrosine Kinase Substrate (HGS))

Alternative Name: HGS (HGS Products)

Synonyms: HRS antibody, Hrs antibody, fi34f05 antibody, zgc:63492 antibody, wu:fi34f05 antibody, Hgr antibody, ZFYVE8 antibody, CG2903 antibody, Dmel\\CG2903 antibody, HRS-2 antibody, Vps27 antibody, hrs antibody, l(2)23AB5 antibody, l(2)23Ad antibody, l(2)23Ad(Hrs) antibody, vps27 antibody, hgs antibody, hepatocyte growth factor-regulated tyrosine kinase substrate antibody, HGF-regulated tyrosine kinase substrate antibody, Hepatocyte growth factor regulated tyrosine kinase substrate antibody, hepatocyte growth factor-regulated tyrosine kinase substrate L homeolog antibody, HGS antibody, Hgs antibody, hgs antibody, Hrs antibody, hgs.L antibody

Background: HGS, hepatocyte growth factor-regulated tyrosine kinase substrate , HGNC:4897, HRS, ZFYVE8, human growth factor-regulated tyrosine kinase substrate

Gene ID: 9146, 15239, 56084

NCBI Accession: NP_004703

Pathways: EGFR Signaling Pathway, CXCR4-mediated Signaling Events, Synaptic Vesicle Exocytosis, EGFR Downregulation