GBA antibody (AA 334-498)

Catalog No. ABIN1858968

Product Details anti-GBA Antibody

Target: GBA (Glucosidase, Beta, Acid (GBA))

Binding Specificity: AA 334-498

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GBA antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Purpose: Polyclonal Antibody to Glucocerebrosidase (GBA)

Specificity: The antibody is a rabbit polyclonal antibody raised against GBA. It has been selected for its ability to recognize GBA in immunohistochemical staining and western blotting.

Cross-Reactivity: Mouse

Purification: Antigen-specific affinity chromatography followed by Protein A affinity chromatography

Immunogen: Recombinant Glucocerebrosidase (GBA) corresdonding to Val334~Val498 with N-terminal His Tag

Isotype: IgG

Application Details

Application Notes:

Western blotting: 0.5-2 μg/mL

1:400-1600 Immunohistochemistry: 5-20 μg/mL

1:40-160 Immunocytochemistry: 5-20 μg/mL

1:40-160 Optimal working dilutions must be determined by end user.

Comment:

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, pH 7.4, containing 0.02 % Sodium azide, 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Expiry Date: 24 months

Target Details for GBA

Target: GBA (Glucosidase, Beta, Acid (GBA))

Alternative Name: Glucocerebrosidase (GBA Products)

Synonyms: GBA1 antibody, GCB antibody, GLUC antibody, BETA-GLUCOSIDASE antibody, T12J13.8 antibody, T12J13_8 antibody, beta glucosidase 25 antibody, PSPTO3318 antibody, PSPTO4290 antibody, GC antibody, GCase antibody, betaGC antibody, glucosylceramidase beta antibody, beta glucosidase 25 antibody, beta-glucosidase antibody, Beta-glucosidase antibody, glucosidase, beta, acid antibody, glucosylceramidase antibody, bglX-2 antibody, GBA antibody, BGLU25 antibody, PSPTO_3318 antibody, bglX antibody, bglA4 antibody, Gba antibody, LOC100399524 antibody, bglA.2 antibody, bglX-2 antibody

Background: GBA1, GCB, GLUC, Imiglucerase, Alglucerase, Beta-glucocerebrosidase, Glucosidase Beta, Acid, β-Glucosidase, D-Glucosyl-N-Acylsphingosine Glucohydrolase

Pathways: Cellular Glucan Metabolic Process