PTPRB antibody (AA 1655-1918)

Catalog No. ABIN1860364

Product Details anti-PTPRB Antibody

Target: PTPRB (Protein tyrosine Phosphatase, Receptor Type, B (PTPRB))

Binding Specificity: AA 1655-1918

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTPRB antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Purpose: Polyclonal Antibody to Protein Tyrosine Phosphatase Receptor Type B (PTPRB)

Specificity: The antibody is a rabbit polyclonal antibody raised against PTPRB. It has been selected for its ability to recognize PTPRB in immunohistochemical staining and western blotting.

Cross-Reactivity: Mouse

Purification: Antigen-specific affinity chromatography followed by Protein A affinity chromatography

Immunogen: Recombinant Protein Tyrosine Phosphatase Receptor Type B (PTPRB) corresdonding to Ala1655~Asp1918 with N-terminal His Tag

Isotype: IgG

Application Details

Application Notes:

Western blotting: 0.5-3 μg/mL

Immunohistochemistry: 5-30 μg/mL

Immunocytochemistry: 5-30 μg/mL

Optimal working dilutions must be determined by end user.

Comment:

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 0.01M PBS, pH 7.4, containing 0.05 % Proclin-300, 50 % glycerol.

Preservative: ProClin

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Expiry Date: 24 months

References for anti-PTPRB antibody (ABIN1860364)

Kim, Park, Kim, Noh, Park, Lie, Kim, Kim, Kwon: "SALM4 regulates angiogenic functions in endothelial cells through VEGFR2 phosphorylation at Tyr1175." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 33, Issue 9, pp. 9842-9857, (2020) (PubMed).

Target Details for PTPRB

Target: PTPRB (Protein tyrosine Phosphatase, Receptor Type, B (PTPRB))

Alternative Name: Protein Tyrosine Phosphatase Receptor Type B (PTPRB Products)

Synonyms: PTPRB antibody, HPTP-BETA antibody, HPTPB antibody, PTPB antibody, R-PTP-BETA antibody, VEPTP antibody, 3230402H02Rik antibody, C130094E24 antibody, Ptpz antibody, Rptpb antibody, VE-PTP antibody, Veptp antibody, protein tyrosine phosphatase, receptor type B antibody, receptor-type tyrosine-protein phosphatase beta antibody, protein tyrosine phosphatase, receptor type, B antibody, PTPRB antibody, LOC100380677 antibody, Ptprb antibody

Background: PTPR-B, HPTP-Beta, HPTPB, PTPB, VE-PTP, R-PTP-Beta, Protein-tyrosine phosphatase beta, Vascular endothelial protein tyrosine phosphatase