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Desmoglein 3 antibody

DSG3 Reactivity: Human WB, IF, IP, IHC (p) Host: Mouse Monoclonal 5G11 unconjugated
Catalog No. ABIN187349
  • Target See all Desmoglein 3 (DSG3) Antibodies
    Desmoglein 3 (DSG3)
    Reactivity
    • 67
    • 21
    • 16
    Human
    Host
    • 61
    • 26
    Mouse
    Clonality
    • 60
    • 27
    Monoclonal
    Conjugate
    • 36
    • 9
    • 8
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Desmoglein 3 antibody is un-conjugated
    Application
    • 64
    • 35
    • 20
    • 18
    • 16
    • 13
    • 13
    • 8
    • 7
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Specificity
    Reacts with the 140 kDa desmoglein 3 protein. Does not cross-react with desmoglein 1 or desmoglein 2. The antibody does not inhibit biological activity of desmoglein 3. Species Reactivity: Human. Others not tested.
    Sterility
    0.2 μm filtered
    Clone
    5G11
    Isotype
    IgG1
    Top Product
    Discover our top product DSG3 Primary Antibody
  • Application Notes
    Immunofluorescence: Use at a 1:10 dilution Immunohistochemistry (paraffin embedded sections) Immunoprecipitation Western blot: Use at a 1:10 dilution The optimal dilution for a specific application should be determined by the researcher.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    1 mL at 100 µg/mL of 0.2 µm filtered antibody solution in PBS containing 0.1% protein stabilizer and 0.02% sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
  • Target
    Desmoglein 3 (DSG3)
    Alternative Name
    Desmoglein-3 (DSG3 Products)
    Synonyms
    DSG3 antibody, CDHF6 antibody, PVA antibody, bal antibody, balding antibody, desmoglein 3 antibody, DSG3 antibody, Dsg3 antibody
    Background
    Desmoglein 3 is a member of the desmosomal cadherin family that comprise the desmogleins and desmocollins. Desmosomes are cell-cell junctions in most epithelial cells and serve to link the intermediate filament cytoskeletons of adjacent cells. Within the desmosome the extracellular domain of desmoglein is essential for calcium dependent heterophilic binding to the desmocollins, whereas the intracellular domain is essential for binding to the desmosomal plaque protein, plakoglobin. Desmoglein 3 is synthesized in both the basal and the lower suprabasal compartments.
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