ABCB4 antibody

Catalog No. ABIN187358

Product Details anti-ABCB4 Antibody

Target: ABCB4 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 (ABCB4))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ABCB4 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificity: P3II-26 reacts with an internal epitope of MDR3 / P-Glycoprotein (ABCB4). P3II-26 does not cross-react with the human MDR1 / P-Glycoprotein. Species Reactivity: Human and guinea pig. Others not tested.

Immunogen: A fusion protein containing a fragment of the MDR3 / P-Glycoprotein comprised of amino acids 629-692 and Glutathione S Transferase.

Clone: P3II-26

Isotype: IgG2b

Application Details

Application Notes: Western blot Immunocytochemistry: Use at a dilution of 1:20-1:50 on acetone-fixed cytospin preparations. Immunohistochemistry: Use at a dilution of 1:20 on acetone-fixed frozen sections, followed by incubation with rabbit anti-mouse IgG and a monoclonal mouse APAAP complex. P3II-26 does not work very well on formaldehyde-fixed paraffin-embedded human tissues. Flow cytometry: Optimal conditions still to be determined. The optimal dilution for a specific application should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 1 mL (>200 tests) or 0.5 mL (>100 tests) monoclonal antibody at ~250 µg IgG/mL in serum-free culture supernatant with protein stabilizer and 0.1% sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Target Details for ABCB4

Target: ABCB4 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 (ABCB4))

Alternative Name: ABCB4 / MDR3 (ABCB4 Products)

Synonyms: ABC21 antibody, GBD1 antibody, ICP3 antibody, MDR2 antibody, MDR2/3 antibody, MDR3 antibody, PFIC-3 antibody, PGY3 antibody, zgc:172149 antibody, Mdr2 antibody, Pgy-2 antibody, Pgy2 antibody, mdr-2 antibody, Pgy3 antibody, ABCB4a antibody, DEFB1 antibody, PGP2 antibody, PGY2 antibody, PGP3 antibody, ABCB4 antibody, RUNDC3B antibody, ATP binding cassette subfamily B member 4 antibody, ATP-binding cassette, sub-family B (MDR/TAP), member 4 antibody, beta-defensin 1-like antibody, ATP-binding cassette, sub-family B (MDR/TAP), member 1B antibody, RUN domain-containing protein 3B antibody, ABCB4 antibody, abcb4 antibody, Abcb4 antibody, LOC100861170 antibody, Abcb1b antibody, LOC101122517 antibody

Pathways: Regulation of Lipid Metabolism by PPARalpha