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Cytochrome C, Somatic (CYCS) antibody

Antigen

Cytochrome C, Somatic (CYCS)
Synonyms
cycs, CYCS, CYC, HCS, THC4, cyc, hcs, cyct, MGC75709, MGC89066, DKFZp468F1016, MGC128356, CYCSA, MGC93634, Cyt-c1, CytC-1, CytC1, Cytc, Cytc-d, DC3, bln, bs30f07.y1, cyt c-d, cyt-c-d, cyt.c, cytochrom ... show more
Clonality Monoclonal (SJL2-4)
Host
Alternatives

Mouse
Reactivity
Alternatives

Goat, Human, Mouse (Murine), Rat (Rattus), Sheep (Ovine)
Application
Alternatives Immunohistochemistry (Frozen Sections) (IHC (fro)), Western Blotting (WB)
Catalog no. ABIN187410
Quantity 0.1 mg
Price 456.00 $   Plus shipping costs $35.00
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anti-Cytochrome C, Somatic (CYCS) antibody

anti-Cytochrome C, Somatic (CYCS) antibody (2)

Additional Information
Application Details Images Alternatives Secondary Antibodies back to top

Alternative name Cytochrome c
Immunogen Horse cytochrome c (aa.1-104).
Isotype IgG2b  (Matching secondary antibodies)
Clone SJL2-4
Description Cytochrome c is translated by cytosolic ribosomes as apocytochrome c, and undergoes subsequent translocation into the mitochondria where a heme group is attached covalently to form holocytochrome c. Cytochrome c is important in the process of oxidative phosphorylation in mitochondria by participating in electron transport. Following exposure of a cell to an apoptotic stimuli, cytochrome c is released from mitochondria into the cytosol, binds Apaf-1 and stimulates activation of proapoptotic caspase-9 and -3. Bcl-2 and Bcl-xL prevent the release of cytochrome c and thereby inhibit apoptosis.
Specificity Recognizes apocytochrome c. Species Reactivity: Human, mouse, rat, goat, sheep and monkey. Others not tested.
Synonyms cycs, CYCS, CYC, HCS, THC4, cyc, hcs, cyct, MGC75709, MGC89066, DKFZp468F1016, MGC128356, CYCSA, MGC93634, Cyt-c1, CytC-1, CytC1, Cytc, Cytc-d, DC3, bln, bs30f07.y1, cyt c-d, cyt-c-d, cyt.c, cytochrome c, ms(2)04445, pDMc02, DmelCG13263, CG13263, Cyt-c2, CytC-2, Cytc-p, DC4, DMc01, cyt c-p, cyt-c-p, l(2)SH1590, pDMc01, DmelCG17903, CG17903

Application Details
Images Alternatives Secondary Antibodies back to top

Purity 95% as determined by SDS-PAGE.
Buffer 100 µg of monoclonal antibody at 1 mg/mL in PBS with 0.02% sodium azide.
Storage Store at 4 °C.Do not freeze.
Research Area Apoptosis/Necrosis, Metabolism
Restrictions For Research Use only

Alternatives
Application Details Images Secondary Antibodies back to top

Alternatives for antigen "Cytochrome C, Somatic (CYCS)", type "Antibodies"
Hosts Rabbit (51), Mouse (17), Sheep (4)
Reactivities Human (55), Rat (Rattus) (38), Mouse (Murine) (34), Horse (Equine) (24), Rabbit (22), Cow (Bovine) (18), Guinea Pig (16), Chicken (15), Dog (Canine) (7), Arabidopsis thaliana (1), Fruit Fly (Drosophila melanogaster) (1), Goat (1), Hamster (1), Lupinus luteus (1), Mammalian (1), Monkey (1), Pig (Porcine) (1), Pigeon (1), Sheep (Ovine) (1)
Applications Western Blotting (WB) (44), Flow Cytometry (FACS) (26), Immunofluorescence (IF) (26), Immunoprecipitation (IP) (15), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (14), ELISA (10), Enzyme Immunoassay (EIA) (9), Immunohistochemistry (Frozen Sections) (IHC (fro)) (6), Immunohistochemistry (IHC) (4), Dot Blot (Dot) (3), Immunodiffusion (ID) (3), Radioimmunoassay (RIA) (3), ELISA (Detection) (2), Functional Studies (Func) (2), Immunocytochemistry (ICC) (2), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Blocking Antibody (Inhibition) (1), Immunoelectron Microscopy (IEM) (1), Intracellular Staining (IS) (1)
Conjugates Biotin (4), Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)