»
Antibodies
»
anti-Lymphotoxin beta Receptor (TNFR Superfamily, Member 3) (LTBR) antibody
Lymphotoxin beta Receptor (TNFR Superfamily, Member 3) (LTBR) antibody
| Antigen |
|
| Synonyms |
CD18, TNFCR, D12S370, TNFR-RP, TNFRSF3, TNFR2-RP, LT-BETA-R, TNF-R-III |
| Clonality |
Monoclonal (4H8 WH2) |
|
Host
|
|
|
Reactivity
|
|
|
Application
|
 Alternatives Flow Cytometry (FACS), Functional Studies (Func)
|
| Catalog no. |
ABIN187584 |
| Quantity |
0.1 mg |
| Price |
630.67 $ Plus shipping costs $35.00
|
| Shipping to |
|
| Availability |
Ships within 7 to 10 Business Days |
|
Alternative name
|
LTBR / TNFR3
|
|
Immunogen
|
Recombinant mouse LTbetaR cysteine-rich region (aa 31-221).
|
|
Isotype
|
IgG2a (Matching secondary antibodies)
|
|
Clone
|
4H8 WH2
|
|
Description
|
The monoclonal antibody to mouse LTbetaR is an agonist that can be used for the investigation of the regulation of BAFF(BlyS), chemokines and integrins using in vivo and tissue culture models, the development of NK cells, and NK T cells, to study the regulation of NF-kappaB family of transcription factors in regulation of inflammation and homeostasis, particularly ReIB NF-kappaB2 pathway.
|
|
Specificity
|
Recognizes mouse LTbetaR Species Reactivity: Mouse. Other species not tested.
|
|
Application Notes
|
Flow cytometry Functional application: Agonist inducing BAFF, chemokines and integrins in vitro and in vivo. Add to cell cultures at 2 µg/mL. For in vivo use, mice are injected intraperitoneally with 50 µg/mL of antibody clone 4H8 WH2 in sterile phosphate saline. The researcher should determine the optimal dilution for a specific application.
|
|
Purity
|
98% as determined by SDS-PAGE.
|
|
Buffer
|
100 µg of liquid monoclonal antibody at 1 mg/mL in PBS.
|
|
Storage
|
Store at 4 °C short term and at -20 °C long term. Aliquot to avoid freeze/thaw cycles.
|
|
Restrictions
|
For Research Use only
|
Alternatives for antigen "Lymphotoxin beta Receptor (TNFR Superfamily, Member 3) (LTBR)", type "Antibodies"
|
Hosts
|
Rat (14), Mouse (2), Rabbit (1)
|
|
Reactivities
|
Mouse (Murine) (12), Human (6)
|
|
Applications
|
Flow Cytometry (FACS) (14), Immunoprecipitation (IP) (3), Western Blotting (WB) (3), ELISA (Detection) (2), Functional Studies (Func) (1), Immunofluorescence (IF) (1)
|
|
Conjugates
|
FITC (3), Biotin (2), PE (2)
|
