Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

Bcl-2 antibody (pThr56)

BCL2 Reactivity: Human DB Host: Rabbit Polyclonal RB30611 unconjugated
Catalog No. ABIN1881106
  • Target See all Bcl-2 (BCL2) Antibodies
    Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))
    Binding Specificity
    • 51
    • 34
    • 23
    • 22
    • 20
    • 18
    • 17
    • 16
    • 16
    • 16
    • 15
    • 14
    • 13
    • 10
    • 8
    • 8
    • 8
    • 8
    • 7
    • 7
    • 7
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pThr56
    Reactivity
    • 443
    • 184
    • 180
    • 38
    • 34
    • 22
    • 22
    • 17
    • 17
    • 16
    • 10
    • 5
    • 5
    • 1
    • 1
    • 1
    Human
    Host
    • 357
    • 111
    • 6
    • 2
    • 1
    Rabbit
    Clonality
    • 353
    • 123
    Polyclonal
    Conjugate
    • 210
    • 34
    • 34
    • 25
    • 24
    • 15
    • 11
    • 11
    • 11
    • 11
    • 11
    • 11
    • 9
    • 9
    • 9
    • 9
    • 9
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Bcl-2 antibody is un-conjugated
    Application
    • 389
    • 192
    • 168
    • 121
    • 107
    • 100
    • 92
    • 69
    • 64
    • 33
    • 26
    • 23
    • 17
    • 8
    • 8
    • 8
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dot Blot (DB)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This bcl-2 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T56 of human bcl-2.
    Clone
    RB30611
    Isotype
    Ig Fraction
    Top Product
    Discover our top product BCL2 Primary Antibody
  • Application Notes
    DB: 1:500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Expiry Date
    6 months
  • Feng, Stachura, White, Gutierrez, Zhang, Sanda, Jette, Testa, Neuberg, Langenau, Kutok, Zon, Traver, Fleming, Kanki, Look: "T-lymphoblastic lymphoma cells express high levels of BCL2, S1P1, and ICAM1, leading to a blockade of tumor cell intravasation." in: Cancer cell, Vol. 18, Issue 4, pp. 353-66, (2010) (PubMed).

  • Target
    Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))
    Alternative Name
    bcl-2 (BCL2 Products)
    Synonyms
    Bcl-2 antibody, PPP1R50 antibody, bcl-2 antibody, AW986256 antibody, C430015F12Rik antibody, D630044D05Rik antibody, D830018M01Rik antibody, BCL-2 antibody, Bcl2 antibody, BCL2, apoptosis regulator antibody, B cell leukemia/lymphoma 2 antibody, B-cell CLL/lymphoma 2a antibody, B-cell CLL/lymphoma 2 protein antibody, BCL2 antibody, Bcl2 antibody, bcl2a antibody, BCL-2 antibody
    Background
    This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends. [provided by RefSeq].
    Molecular Weight
    26266
    NCBI Accession
    NP_000624
    UniProt
    P10415
    Pathways
    MAPK Signaling, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Autophagy, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling
You are here:
Support