C1GALT1 antibody (AA 115-144)

Catalog No. ABIN1881126

Product Details anti-C1GALT1 Antibody

Target: C1GALT1 (Core 1 Synthase, Glycoprotein-N-Acetylgalactosamine 3-beta-Galactosyltransferase, 1 (C1GALT1))

Binding Specificity: AA 115-144

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C1GALT1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This C1GALT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 115-144 amino acids from the Central region of human C1GALT1.

Clone: RB43864

Isotype: IgG

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-C1GALT1 antibody (ABIN1881126)

Scherer, Cheung, MacDonald, Osborne, Nakabayashi, Herbrick, Carson, Parker-Katiraee, Skaug, Khaja, Zhang, Hudek, Li, Haddad, Duggan, Fernandez, Kanematsu, Gentles, Christopoulos, Choufani, Kwasnicka et al.: "Human chromosome 7: DNA sequence and biology. ..." in: Science (New York, N.Y.), Vol. 300, Issue 5620, pp. 767-72, (2003) (PubMed).

Ju, Brewer, DSouza, Cummings, Canfield: "Cloning and expression of human core 1 beta1,3-galactosyltransferase." in: The Journal of biological chemistry, Vol. 277, Issue 1, pp. 178-86, (2002) (PubMed).

Ju, Cummings: "A unique molecular chaperone Cosmc required for activity of the mammalian core 1 beta 3-galactosyltransferase." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16613-8, (2002) (PubMed).

Target Details for C1GALT1

Target: C1GALT1 (Core 1 Synthase, Glycoprotein-N-Acetylgalactosamine 3-beta-Galactosyltransferase, 1 (C1GALT1))

Alternative Name: C1GALT1 (C1GALT1 Products)

Synonyms: C1GALT antibody, T-synthase antibody, 2210410E06Rik antibody, AV284120 antibody, c1galt1 antibody, fa98f05 antibody, zgc:66485 antibody, wu:fa98f05 antibody, C1GALT1 antibody, C1GalT1-A antibody, Core 1 beta3-Gal-T1-A antibody, wu:fi11c09 antibody, zgc:153355 antibody, core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 antibody, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 L homeolog antibody, core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1 antibody, core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1b antibody, core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1a antibody, C1GALT1 antibody, LOC100496837.L antibody, C1galt1 antibody, c1galt1b antibody, c1galt1a antibody

Background: Glycosyltransferase that generates the core 1 O-glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins. Plays a central role in many processes, such as angiogenesis, thrombopoiesis and kidney homeostasis development.

Molecular Weight: 42203

NCBI Accession: NP_064541

UniProt: Q9NS00