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eIF4EBP2 antibody (C-Term)

EIF4EBP2 Reactivity: Human WB Host: Rabbit Polyclonal RB41859 unconjugated
Catalog No. ABIN1881292
  • Target See all eIF4EBP2 (EIF4EBP2) Antibodies
    eIF4EBP2 (EIF4EBP2) (Eukaryotic Translation Initiation Factor 4E Binding Protein 2 (EIF4EBP2))
    Binding Specificity
    • 15
    • 13
    • 7
    • 6
    • 3
    • 2
    • 1
    • 1
    AA 87-115, C-Term
    Reactivity
    • 47
    • 7
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 44
    • 3
    Rabbit
    Clonality
    • 45
    • 2
    Polyclonal
    Conjugate
    • 17
    • 5
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This eIF4EBP2 antibody is un-conjugated
    Application
    • 28
    • 27
    • 13
    • 13
    • 10
    • 6
    • 3
    Western Blotting (WB)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This EIF4EBP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 87-115 amino acids from the C-terminal region of human EIF4EBP2.
    Clone
    RB41859
    Isotype
    Ig Fraction
    Top Product
    Discover our top product EIF4EBP2 Primary Antibody
  • Application Notes
    WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Expiry Date
    6 months
  • Bidinosti, Martineau, Frank, Sonenberg: "Repair of isoaspartate formation modulates the interaction of deamidated 4E-BP2 with mTORC1 in brain." in: The Journal of biological chemistry, Vol. 285, Issue 25, pp. 19402-8, (2010) (PubMed).

    Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, (2010) (PubMed).

    Gingras, Sonenberg: "Adenovirus infection inactivates the translational inhibitors 4E-BP1 and 4E-BP2." in: Virology, Vol. 237, Issue 1, pp. 182-6, (1997) (PubMed).

  • Target
    eIF4EBP2 (EIF4EBP2) (Eukaryotic Translation Initiation Factor 4E Binding Protein 2 (EIF4EBP2))
    Alternative Name
    EIF4EBP2 (EIF4EBP2 Products)
    Synonyms
    4ebp2 antibody, MGC75579 antibody, wu:fa55e11 antibody, wu:fp45e09 antibody, MGC78987 antibody, EIF4EBP2 antibody, eIF-4E antibody, Tb06.28P18.1010 antibody, 4EBP2 antibody, PHASII antibody, 2810011I19Rik antibody, 4E-BP2 antibody, AA792569 antibody, BC010348 antibody, PHAS-II antibody, eukaryotic translation initiation factor 4E binding protein 2 antibody, eukaryotic translation initiation factor 4E binding protein 2 L homeolog antibody, eukaryotic initiation factor 4E antibody, eukaryotic translation initiation factor 4E antibody, putative eukaryotic translation initiation factor 4e antibody, eif4ebp2 antibody, Eif4ebp2 antibody, eif4ebp2.L antibody, EIF4EBP2 antibody, eIF-4E antibody, Tb927.6.1870 antibody, LMJF_30_0450 antibody
    Background
    This gene encodes a member of the eukaryotic translation initiation factor 4E binding protein family. The gene products of this family bind eIF4E and inhibit translation initiation. However, insulin and other growth factors can release this inhibition via a phosphorylation-dependent disruption of their binding to eIF4E. Regulation of protein production through these gene products have been implicated in cell proliferation, cell differentiation and viral infection.
    Molecular Weight
    12939
    NCBI Accession
    NP_004087
    UniProt
    Q13542
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