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FMO5 antibody (C-Term)

FMO5 Reactivity: Human WB Host: Rabbit Polyclonal RB42789 unconjugated
Catalog No. ABIN1881348
  • Target See all FMO5 Antibodies
    FMO5 (Flavin Containing Monooxygenase 5 (FMO5))
    Binding Specificity
    • 15
    • 13
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    AA 474-502, C-Term
    Reactivity
    • 41
    • 22
    • 20
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 39
    • 2
    Rabbit
    Clonality
    • 41
    Polyclonal
    Conjugate
    • 17
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FMO5 antibody is un-conjugated
    Application
    • 39
    • 20
    • 13
    • 13
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This FMO5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 474-502 amino acids from the C-terminal region of human FMO5.
    Clone
    RB42789
    Isotype
    Ig Fraction
    Top Product
    Discover our top product FMO5 Primary Antibody
  • Application Notes
    WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Expiry Date
    6 months
  • Ross, Katzov-Eckert, Dubé, Brooks, Rassekh, Barhdadi, Feroz-Zada, Visscher, Brown, Rieder, Rogers, Phillips, Carleton, Hayden: "Genetic variants in TPMT and COMT are associated with hearing loss in children receiving cisplatin chemotherapy." in: Nature genetics, Vol. 41, Issue 12, pp. 1345-9, (2009) (PubMed).

    Furnes, Feng, Sommer, Schlenk: "Identification of novel variants of the flavin-containing monooxygenase gene family in African Americans." in: Drug metabolism and disposition: the biological fate of chemicals, Vol. 31, Issue 2, pp. 187-93, (2003) (PubMed).

  • Target
    FMO5 (Flavin Containing Monooxygenase 5 (FMO5))
    Alternative Name
    FMO5 (FMO5 Products)
    Synonyms
    MGC68633 antibody, MGC108355 antibody, sb:cb1007 antibody, wu:fc05b01 antibody, wu:fk47g04 antibody, 5033418D19Rik antibody, AI195026 antibody, flavin containing monooxygenase 5 S homeolog antibody, flavin containing monooxygenase 5 antibody, fmo5.S antibody, fmo5 antibody, MCYG_00559 antibody, FMO5 antibody, Fmo5 antibody
    Background
    Metabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man resulting in a small subpopulation with reduced TMA N-oxidation capacity resulting in fish odor syndrome Trimethylaminuria. Three forms of the enzyme, FMO1 found in fetal liver, FMO2 found in adult liver, and FMO3 are encoded by genes clustered in the 1q23-q25 region. Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyzes the oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics. Alternative splicing results in multiple transcript variants.
    Molecular Weight
    60221
    NCBI Accession
    NP_001138301, NP_001138302, NP_001452
    UniProt
    P49326
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