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GATM antibody (C-Term)

GATM Reactivity: Human WB Host: Rabbit Polyclonal RB41023 unconjugated
Catalog No. ABIN1881365
  • Target See all GATM Antibodies
    GATM (Glycine Amidinotransferase (L-Arginine:glycine Amidinotransferase) (GATM))
    Binding Specificity
    • 15
    • 13
    • 8
    • 7
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    AA 350-378, C-Term
    Reactivity
    • 61
    • 13
    • 12
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 58
    • 4
    Rabbit
    Clonality
    • 60
    • 2
    Polyclonal
    Conjugate
    • 21
    • 6
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This GATM antibody is un-conjugated
    Application
    • 54
    • 32
    • 22
    • 13
    • 13
    • 8
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Predicted Reactivity
    B, Pr, M, Pig, Rat
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This GATM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 350-378 amino acids from the C-terminal region of human GATM.
    Clone
    RB41023
    Isotype
    Ig Fraction
    Top Product
    Discover our top product GATM Primary Antibody
  • Application Notes
    WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Expiry Date
    6 months
  • Köttgen, Glazer, Dehghan, Hwang, Katz, Li, Yang, Gudnason, Launer, Harris, Smith, Arking, Astor, Boerwinkle, Ehret, Ruczinski: "Multiple loci associated with indices of renal function and chronic kidney disease." in: Nature genetics, Vol. 41, Issue 6, pp. 712-7, (2010) (PubMed).

    Köttgen, Pattaro, Böger, Fuchsberger, Olden, Glazer, Parsa, Gao, Yang, Smith, OConnell, Li, Schmidt, Tanaka, Isaacs, Ketkar, Hwang, Johnson, Dehghan, Teumer, Paré, Atkinson, Zeller, Lohman et al.: "New loci associated with kidney function and chronic kidney disease...." in: Nature genetics, Vol. 42, Issue 5, pp. 376-84, (2010) (PubMed).

    Lion-François, Cheillan, Pitelet, Acquaviva-Bourdain, Bussy, Cotton, Guibaud, Gérard, Rivier, Vianey-Saban, Jakobs, Salomons, des Portes: "High frequency of creatine deficiency syndromes in patients with unexplained mental retardation." in: Neurology, Vol. 67, Issue 9, pp. 1713-4, (2006) (PubMed).

  • Target
    GATM (Glycine Amidinotransferase (L-Arginine:glycine Amidinotransferase) (GATM))
    Alternative Name
    GATM (GATM Products)
    Synonyms
    AT antibody, AGAT antibody, CCDS3 antibody, 1810003P21Rik antibody, AI314789 antibody, cb409 antibody, wu:fa08a06 antibody, zgc:65855 antibody, glycine amidinotransferase (L-arginine:glycine amidinotransferase) L homeolog antibody, glycine amidinotransferase antibody, glycine amidinotransferase (L-arginine:glycine amidinotransferase) antibody, gatm.L antibody, GATM antibody, Gatm antibody, gatm antibody
    Background
    This gene encodes a mitochondrial enzyme that belongs to the amidinotransferase family. This enzyme is involved in creatine biosynthesis, whereby it catalyzes the transfer of a guanido group from L-arginine to glycine, resulting in guanidinoacetic acid, the immediate precursor of creatine. Mutations in this gene cause arginine:glycine amidinotransferase deficiency, an inborn error of creatine synthesis characterized by mental retardation, language impairment, and behavioral disorders.
    Molecular Weight
    48455
    NCBI Accession
    NP_001473
    UniProt
    P50440
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