HBZ antibody (C-Term)

Catalog No. ABIN1881404

Product Details anti-HBZ Antibody

Target: HBZ (Hemoglobin, zeta (HBZ))

Binding Specificity: AA 95-123, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HBZ antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This HBZ antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 95-123 amino acids from the C-terminal region of human HBZ.

Clone: RB41010

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-HBZ antibody (ABIN1881404)

He, Russell: "Effect of zeta-globin substitution on the O2-transport properties of Hb S in vitro and in vivo." in: Biochemical and biophysical research communications, Vol. 325, Issue 4, pp. 1376-82, (2004) (PubMed).

Kidd, Russell, Watmough, Baker, Brittain: "The role of beta chains in the control of the hemoglobin oxygen binding function: chimeric human/mouse proteins, structure, and function." in: Biochemistry, Vol. 40, Issue 51, pp. 15669-75, (2001) (PubMed).

Lau, Kwok, Chui, Wong, Luo, Tang: "Embryonic and fetal globins are expressed in adult erythroid progenitor cells and in erythroid cell cultures." in: Prenatal diagnosis, Vol. 21, Issue 7, pp. 529-39, (2001) (PubMed).

Century, Fenichel, Horowitz: "The concentrations of water, sodium and potassium in the nucleus and cytoplasm of amphibian oocytes." in: Journal of cell science, Vol. 7, Issue 1, pp. 5-13, (1970) (PubMed).

Target Details for HBZ

Target: HBZ (Hemoglobin, zeta (HBZ))

Alternative Name: HBZ (HBZ Products)

Synonyms: RGD1307486 antibody, HBZ antibody, hba-l1 antibody, MGC82702 antibody, RA_M008_JSM295ECF antibody, hemoglobin, zeta antibody, hemoglobin subunit zeta antibody, HBZ antibody, Hbz antibody, HBZ1 antibody, hbz antibody

Background: Zeta-globin is an alpha-like hemoglobin. The zeta-globin polypeptide is synthesized in the yolk sac of the early embryo, while alpha-globin is produced throughout fetal and adult life. The zeta-globin gene is a member of the human alpha-globin gene cluster that includes five functional genes and two pseudogenes. The order of genes is: 5' - zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 -alpha-1 - theta1 - 3'.

Molecular Weight: 15637

NCBI Accession: NP_005323

UniProt: P02008