HOXA10 antibody (AA 252-281)

Catalog No. ABIN1881425

Product Details anti-HOXA10 Antibody

Target: HOXA10 (Homeobox A10 (HOXA10))

Binding Specificity: AA 252-281

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HOXA10 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This Mouse Hoxa10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 252-281 amino acids from the Central region of mouse Hoxa10.

Clone: RB39509

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-HOXA10 antibody (ABIN1881425)

Gordon, Hassan, Saini, Montecino, van Wijnen, Stein, Stein, Lian: "Pbx1 represses osteoblastogenesis by blocking Hoxa10-mediated recruitment of chromatin remodeling factors." in: Molecular and cellular biology, Vol. 30, Issue 14, pp. 3531-41, (2010) (PubMed).

Das: "Regional development of uterine decidualization: molecular signaling by Hoxa-10." in: Molecular reproduction and development, Vol. 77, Issue 5, pp. 387-96, (2010) (PubMed).

Vinagre, Moncaut, Carapuço, Nóvoa, Bom, Mallo: "Evidence for a myotomal Hox/Myf cascade governing nonautonomous control of rib specification within global vertebral domains." in: Developmental cell, Vol. 18, Issue 4, pp. 655-61, (2010) (PubMed).

Target Details for HOXA10

Target: HOXA10 (Homeobox A10 (HOXA10))

Alternative Name: Hoxa10 (HOXA10 Products)

Background: In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of a cluster on chromosome 6 and encodes a DNA-binding transcription factor that may regulate gene expression, morphogenesis, and differentiation. More specifically, it may function in fertility, embryo viability, and regulation of hematopoietic lineage commitment. Alternatively spliced transcript variants encoding different isoforms have been described.

Molecular Weight: 43292

NCBI Accession: NP_001116422, NP_032289

UniProt: P31310