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ING2 antibody (AA 112-141)

ING2 Reactivity: Human WB Host: Rabbit Polyclonal RB40520 unconjugated
Catalog No. ABIN1881460
  • Target See all ING2 Antibodies
    ING2 (Inhibitor of Growth Family, Member 2 (ING2))
    Binding Specificity
    • 6
    • 6
    • 6
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    AA 112-141
    Reactivity
    • 32
    • 12
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 26
    • 5
    • 1
    Rabbit
    Clonality
    • 28
    • 4
    Polyclonal
    Conjugate
    • 15
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ING2 antibody is un-conjugated
    Application
    • 24
    • 19
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This ING2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 112-141 amino acids from the Central region of human ING2.
    Clone
    RB40520
    Isotype
    Ig Fraction
    Top Product
    Discover our top product ING2 Primary Antibody
  • Application Notes
    WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Expiry Date
    6 months
  • Ythier, Larrieu, Binet, Binda, Brambilla, Gazzeri, Pedeux: "Sumoylation of ING2 regulates the transcription mediated by Sin3A." in: Oncogene, Vol. 29, Issue 44, pp. 5946-56, (2010) (PubMed).

    Larrieu, Ythier, Binet, Brambilla, Brambilla, Sengupta, Pedeux: "ING2 controls the progression of DNA replication forks to maintain genome stability." in: EMBO reports, Vol. 10, Issue 10, pp. 1168-74, (2009) (PubMed).

    Kumamoto, Fujita, Kurotani, Saito, Unoki, Hagiwara, Shiga, Bowman, Yanaihara, Okamura, Nagashima, Miyamoto, Takenoshita, Yokota, Harris: "ING2 is upregulated in colon cancer and increases invasion by enhanced MMP13 expression." in: International journal of cancer. Journal international du cancer, Vol. 125, Issue 6, pp. 1306-15, (2009) (PubMed).

    Borkosky, Gunduz, Nagatsuka, Beder, Gunduz, Ali, Rodriguez, Cilek, Tominaga, Yamanaka, Shimizu, Nagai: "Frequent deletion of ING2 locus at 4q35.1 associates with advanced tumor stage in head and neck squamous cell carcinoma." in: Journal of cancer research and clinical oncology, Vol. 135, Issue 5, pp. 703-13, (2009) (PubMed).

    Unoki, Kumamoto, Robles, Shen, Zheng, Harris: "A novel ING2 isoform, ING2b, synergizes with ING2a to prevent cell cycle arrest and apoptosis." in: FEBS letters, Vol. 582, Issue 28, pp. 3868-74, (2008) (PubMed).

  • Target
    ING2 (Inhibitor of Growth Family, Member 2 (ING2))
    Alternative Name
    ING2 (ING2 Products)
    Synonyms
    ING1L antibody, p33ING2 antibody, 2810011M06Rik antibody, Ing1l antibody, Ing2b antibody, P33ING2 antibody, ING2 antibody, INGX antibody, wu:fe11c08 antibody, zgc:92346 antibody, ING1Lp antibody, ing2 antibody, xing2 antibody, inhibitor of growth family member 2 antibody, inhibitor of growth family, member 2 antibody, inhibitor of growth family member 2 S homeolog antibody, inhibitor of growth family member 2 L homeolog antibody, ING2 antibody, Ing2 antibody, ing2.S antibody, ing2 antibody, ing2.L antibody
    Background
    This gene is a member of the inhibitor of growth (ING) family. Members of the ING family associate with and modulate the activity of histone acetyltransferase (HAT) and histone deacetylase (HDAC) complexes and function in DNA repair and apoptosis.
    Molecular Weight
    32808
    NCBI Accession
    NP_001555
    UniProt
    Q9H160
    Pathways
    Chromatin Binding, Autophagy, Negative Regulation of intrinsic apoptotic Signaling
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