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PCSK5 antibody (N-Term)

PCSK5 Reactivity: Human WB Host: Rabbit Polyclonal RB41935 unconjugated
Catalog No. ABIN1881639
  • Target See all PCSK5 Antibodies
    PCSK5 (Proprotein Convertase Subtilisin/kexin Type 5 (PCSK5))
    Binding Specificity
    • 13
    • 6
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 95-124, N-Term
    Reactivity
    • 33
    • 16
    • 11
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 36
    • 1
    • 1
    Rabbit
    Clonality
    • 37
    • 1
    Polyclonal
    Conjugate
    • 13
    • 6
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PCSK5 antibody is un-conjugated
    Application
    • 24
    • 20
    • 5
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This PCSK5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 95-124 amino acids from the N-terminal region of human PCSK5.
    Clone
    RB41935
    Isotype
    Ig Fraction
    Top Product
    Discover our top product PCSK5 Primary Antibody
  • Application Notes
    WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Expiry Date
    6 months
  • Heng, Paule, Hardman, Li, Singh, Rainczuk, Stephens, Nie: "Posttranslational activation of bone morphogenetic protein 2 is mediated by proprotein convertase 6 during decidualization for pregnancy establishment." in: Endocrinology, Vol. 151, Issue 8, pp. 3909-17, (2010) (PubMed).

    Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, (2010) (PubMed).

    Iatan, Dastani, Do, Weissglas-Volkov, Ruel, Lee, Huertas-Vazquez, Taskinen, Prat, Seidah, Pajukanta, Engert, Genest: "Genetic variation at the proprotein convertase subtilisin/kexin type 5 gene modulates high-density lipoprotein cholesterol levels." in: Circulation. Cardiovascular genetics, Vol. 2, Issue 5, pp. 467-75, (2009) (PubMed).

  • Target
    PCSK5 (Proprotein Convertase Subtilisin/kexin Type 5 (PCSK5))
    Alternative Name
    PCSK5 (PCSK5 Products)
    Synonyms
    PC5 antibody, PC6 antibody, PC6A antibody, SPC6 antibody, subtilase antibody, PC5/6A antibody, PC5A antibody, b2b1549Clo antibody, b2b585Clo antibody, Pc5 antibody, fur2 antibody, spc6 antibody, spc6A antibody, MGC98915 antibody, PCSK5 antibody, pc6 antibody, spc6a antibody, pcsk5 antibody, zgc:165659 antibody, proprotein convertase subtilisin/kexin type 5 antibody, proprotein convertase subtilisin/kexin type 5 S homeolog antibody, proprotein convertase subtilisin/kexin type 5b antibody, PCSK5 antibody, Pcsk5 antibody, pcsk5.S antibody, LOC528098 antibody, pcsk5 antibody, pcsk5b antibody
    Background
    The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein mediates posttranslational endoproteolytic processing for several integrin alpha subunits. It is thought to process prorenin, pro-membrane type-1 matrix metalloproteinase and HIV-1 glycoprotein gp160. Multiple transcript variants encoding different isoforms have been found for this gene.
    Molecular Weight
    206942
    NCBI Accession
    NP_001177411, NP_006191
    UniProt
    Q92824
    Pathways
    Neurotrophin Signaling Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones
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