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POLR2G antibody (C-Term)

POLR2G Reactivity: Human WB Host: Rabbit Polyclonal RB42404 unconjugated
Catalog No. ABIN1881671
  • Target See all POLR2G Antibodies
    POLR2G (Polymerase (RNA) II (DNA Directed) Polypeptide G (POLR2G))
    Binding Specificity
    • 8
    • 8
    • 7
    • 7
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 125-154, C-Term
    Reactivity
    • 42
    • 11
    • 10
    • 1
    Human
    Host
    • 38
    • 3
    • 1
    Rabbit
    Clonality
    • 41
    • 1
    Polyclonal
    Conjugate
    • 17
    • 5
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This POLR2G antibody is un-conjugated
    Application
    • 31
    • 24
    • 15
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Predicted Reactivity
    B, Zf, M, Rat
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This POLR2G antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 125-154 amino acids from the C-terminal region of human POLR2G.
    Clone
    RB42404
    Isotype
    Ig Fraction
    Top Product
    Discover our top product POLR2G Primary Antibody
  • Application Notes
    WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Expiry Date
    6 months
  • Cojocaru, Jeronimo, Forget, Bouchard, Bergeron, Côte, Poirier, Greenblatt, Coulombe: "Genomic location of the human RNA polymerase II general machinery: evidence for a role of TFIIF and Rpb7 at both early and late stages of transcription." in: The Biochemical journal, Vol. 409, Issue 1, pp. 139-47, (2007) (PubMed).

    Ujvári, Luse: "RNA emerging from the active site of RNA polymerase II interacts with the Rpb7 subunit." in: Nature structural & molecular biology, Vol. 13, Issue 1, pp. 49-54, (2006) (PubMed).

    Meka, Werner, Cordell, Onesti, Brick: "Crystal structure and RNA binding of the Rpb4/Rpb7 subunits of human RNA polymerase II." in: Nucleic acids research, Vol. 33, Issue 19, pp. 6435-44, (2005) (PubMed).

    Zhou, Deng, Kashanchi, Brady, Shatkin, Kumar: "The Tat/TAR-dependent phosphorylation of RNA polymerase II C-terminal domain stimulates cotranscriptional capping of HIV-1 mRNA." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 22, pp. 12666-71, (2003) (PubMed).

  • Target
    POLR2G (Polymerase (RNA) II (DNA Directed) Polypeptide G (POLR2G))
    Alternative Name
    POLR2G (POLR2G Products)
    Synonyms
    RPB19 antibody, RPB7 antibody, hRPB19 antibody, hsRPB7 antibody, Rpb7 antibody, POLR2G antibody, 2410046K11Rik antibody, A230108L04Rik antibody, C76415 antibody, RBP7 antibody, Rpo2-7l antibody, RNA polymerase II subunit G antibody, polymerase (RNA) II (DNA directed) polypeptide G antibody, polymerase (RNA) II (DNA directed) polypeptide G L homeolog antibody, POLR2G antibody, Polr2g antibody, polr2g antibody, polr2g.L antibody
    Background
    This gene encodes the seventh largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The protein functions in transcription initiation, and is also thought to help stabilize transcribing polyermase molecules during elongation.
    Molecular Weight
    19294
    NCBI Accession
    NP_002687
    UniProt
    P62487
    Pathways
    Regulatory RNA Pathways
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