RBMY1A1 antibody (C-Term)

Catalog No. ABIN1881734

Product Details anti-RBMY1A1 Antibody

Target: RBMY1A1 (RNA Binding Motif Protein, Y-Linked Family 1 Member A1 (RBMY1A1))

Binding Specificity: AA 468-496, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RBMY1A1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This RBMY1A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 468-496 amino acids from the C-terminal region of human RBMY1A1.

Clone: RB41568

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-RBMY1A1 antibody (ABIN1881734)

Dreumont, Bourgeois, Lejeune, Liu, Ehrmann, Elliott, Stévenin: "Human RBMY regulates germline-specific splicing events by modulating the function of the serine/arginine-rich proteins 9G8 and Tra2-{beta}." in: Journal of cell science, Vol. 123, Issue Pt 1, pp. 40-50, (2009) (PubMed).

Skrisovska, Bourgeois, Stefl, Grellscheid, Kister, Wenter, Elliott, Stevenin, Allain: "The testis-specific human protein RBMY recognizes RNA through a novel mode of interaction." in: EMBO reports, Vol. 8, Issue 4, pp. 372-9, (2007) (PubMed).

Lavery, Glennon, Houghton, Nolan, Egan, Maher: "Investigation of DAZ and RBMY1 gene expression in human testis by quantitative real-time PCR." in: Archives of andrology, Vol. 53, Issue 2, pp. 71-3, (2007) (PubMed).

Target Details for RBMY1A1

Target: RBMY1A1 (RNA Binding Motif Protein, Y-Linked Family 1 Member A1 (RBMY1A1))

Alternative Name: RBMY1A1 (RBMY1A1 Products)

Background: This gene encodes a protein containing an RNA-binding motif in the N-terminus and four SRGY (serine, arginine, glycine, tyrosine) boxes in the C-terminus. Multiple copies of this gene are found in the AZFb azoospermia factor region of chromosome Y and the encoded protein is thought to be involved in spermatogenesis. Most copies of this locus are pseudogenes, although six highly similar copies have full-length ORFs and are considered functional. Four functional copies of this gene are found within inverted repeat IR2, two functional copies of this gene are found in palindrome P3, along with two copies of PTPN13-like, Y-linked. [provided by RefSeq].

Molecular Weight: 55784

NCBI Accession: NP_005049

UniProt: P0DJD3