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SF3B4 antibody (AA 158-187)

SF3B4 Reactivity: Human WB Host: Rabbit Polyclonal RB40410 unconjugated
Catalog No. ABIN1881796
  • Target See all SF3B4 Antibodies
    SF3B4 (Splicing Factor 3b, Subunit 4, 49kDa (SF3B4))
    Binding Specificity
    • 9
    • 6
    • 6
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 158-187
    Reactivity
    • 40
    • 20
    • 19
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 35
    • 5
    • 1
    Rabbit
    Clonality
    • 36
    • 5
    Polyclonal
    Conjugate
    • 24
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SF3B4 antibody is un-conjugated
    Application
    • 34
    • 24
    • 10
    • 4
    • 4
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Predicted Reactivity
    M, Rat
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This SF3B4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 158-187 amino acids from the Central region of human SF3B4.
    Clone
    RB40410
    Isotype
    Ig Fraction
    Top Product
    Discover our top product SF3B4 Primary Antibody
  • Application Notes
    WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Expiry Date
    6 months
  • Gudbjartsson, Walters, Thorleifsson, Stefansson, Halldorsson, Zusmanovich, Sulem, Thorlacius, Gylfason, Steinberg, Helgadottir, Ingason, Steinthorsdottir, Olafsdottir, Olafsdottir, Jonsson et al.: "Many sequence variants affecting diversity of adult human height." in: Nature genetics, Vol. 40, Issue 5, pp. 609-15, (2008) (PubMed).

    Watanabe, Shionyu, Kimura, Kimata, Watanabe: "Splicing factor 3b subunit 4 binds BMPR-IA and inhibits osteochondral cell differentiation." in: The Journal of biological chemistry, Vol. 282, Issue 28, pp. 20728-38, (2007) (PubMed).

    Wu, Ma, Brown, Geisler, Li, Tzeng, Jia, Jurisica, Li: "Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening." in: Proteomics, Vol. 7, Issue 11, pp. 1775-85, (2007) (PubMed).

  • Target
    SF3B4 (Splicing Factor 3b, Subunit 4, 49kDa (SF3B4))
    Alternative Name
    SF3B4 (SF3B4 Products)
    Synonyms
    chunp6902 antibody, fb36a04 antibody, wu:fb36a04 antibody, 49kDa antibody, SF3b49 antibody, SF3b50 antibody, Sap49 antibody, spx antibody, AFD1 antibody, Hsh49 antibody, SAP49 antibody, Splicing factor 3B subunit 4 antibody, splicing factor 3b, subunit 4 antibody, splicing factor 3b subunit 4 S homeolog antibody, splicing factor 3b subunit 4 antibody, sap-49 antibody, sf3b4 antibody, Sf3b4 antibody, sf3b4.S antibody, SF3B4 antibody
    Background
    This gene encodes one of four subunits of the splicing factor 3B. The protein encoded by this gene cross-links to a region in the pre-mRNA immediately upstream of the branchpoint sequence in pre-mRNA in the prespliceosomal complex A. It also may be involved in the assembly of the B, C and E spliceosomal complexes. In addition to RNA-binding activity, this protein interacts directly and highly specifically with subunit 2 of the splicing factor 3B. This protein contains two N-terminal RNA-recognition motifs (RRMs), consistent with the observation that it binds directly to pre-mRNA.
    Molecular Weight
    44386
    NCBI Accession
    NP_005841
    UniProt
    Q15427
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