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ULK1 antibody (pSer467)

ULK1 Reactivity: Human DB Host: Rabbit Polyclonal RB30636 unconjugated
Catalog No. ABIN1881981
  • Target See all ULK1 Antibodies
    ULK1 (Unc-51 Like Kinase 1 (ULK1))
    Binding Specificity
    • 25
    • 16
    • 16
    • 14
    • 13
    • 11
    • 9
    • 9
    • 8
    • 8
    • 8
    • 8
    • 7
    • 7
    • 7
    • 7
    • 6
    • 6
    • 6
    • 6
    • 5
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer467
    Reactivity
    • 193
    • 77
    • 66
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 196
    • 3
    • 2
    Rabbit
    Clonality
    • 189
    • 12
    Polyclonal
    Conjugate
    • 54
    • 23
    • 19
    • 18
    • 13
    • 11
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This ULK1 antibody is un-conjugated
    Application
    • 112
    • 95
    • 30
    • 26
    • 26
    • 24
    • 20
    • 12
    • 10
    • 9
    • 6
    • 2
    • 2
    • 1
    Dot Blot (DB)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This ULK1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S467 of human ULK1.
    Clone
    RB30636
    Isotype
    Ig Fraction
    Top Product
    Discover our top product ULK1 Primary Antibody
  • Application Notes
    DB: 1:500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Expiry Date
    6 months
  • Mercer, Kaliappan, Dennis: "A novel, human Atg13 binding protein, Atg101, interacts with ULK1 and is essential for macroautophagy." in: Autophagy, Vol. 5, Issue 5, pp. 649-62, (2009) (PubMed).

    Ganley, Lam, Wang, Ding, Chen, Jiang: "ULK1.ATG13.FIP200 complex mediates mTOR signaling and is essential for autophagy." in: The Journal of biological chemistry, Vol. 284, Issue 18, pp. 12297-305, (2009) (PubMed).

    Jung, Jun, Ro, Kim, Otto, Cao, Kundu, Kim: "ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery." in: Molecular biology of the cell, Vol. 20, Issue 7, pp. 1992-2003, (2009) (PubMed).

    Hosokawa, Hara, Kaizuka, Kishi, Takamura, Miura, Iemura, Natsume, Takehana, Yamada, Guan, Oshiro, Mizushima: "Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy." in: Molecular biology of the cell, Vol. 20, Issue 7, pp. 1981-91, (2009) (PubMed).

  • Target
    ULK1 (Unc-51 Like Kinase 1 (ULK1))
    Alternative Name
    ULK1 (ULK1 Products)
    Synonyms
    ATG1 antibody, ATG1A antibody, UNC51 antibody, Unc51.1 antibody, hATG1 antibody, si:dkey-11o18.7 antibody, ulk1 antibody, ULK1 antibody, AU041434 antibody, mKIAA0722 antibody, zgc:195008 antibody, unc-51 like autophagy activating kinase 1 antibody, unc-51 like kinase 1 antibody, unc-51 like autophagy activating kinase 1a antibody, ULK1 antibody, Ulk1 antibody, ulk1b antibody, ulk1a antibody
    Background
    ULK1 is involved in autophagy. Required for autophagosome formation (By similarity). Target of the TOR kinase signaling pathway that regulates autophagy through the control of phosphorylation status of ATG13/KIAA0652 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex (By similarity). Phosphorylates ATG13/KIAA0652. Involved in axon growth (By similarity). Plays an essential role in neurite extension of cerebellar granule cells (By similarity).
    Molecular Weight
    112631
    NCBI Accession
    NP_003556
    UniProt
    O75385
    Pathways
    Regulation of Cell Size, Autophagy
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